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Merck
CN

PCC100C05

Pellicon®胶囊，带Ultracel®膜

pore size 100 kDa, C Screen, 0.5 m2

别名:

Pellicon® Capsule with Ultracel® Membrane

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UNSPSC Code:
41104903

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产品名称

Pellicon®胶囊，带Ultracel®膜, pore size 100 kDa, C Screen, 0.5 m2

material

EPDM rubber seal
PPO/PS blend (core)
PPO/PS blend housing
TPE seal
composite regenerated cellulose (CRC) membrane
epoxy adhesive
polyester screen
polypropylene screen
polyurethane adhesive

sterility

sterile; γ-irradiated

product line

Pellicon®

storage condition

room temperature (15-30°C)

parameter

4-6 L/min-m2 flow rate
45 psi max. transmembrane pressure (3.1 bar) at 4-30 °C (Forward)
80 psi max. inlet pressure (5.5 bar) at 4 - 30 °C

technique(s)

ultrafiltration: suitable

L

35.3 cm (13.9 in.)

diam.

5.7 cm (2.3 in.)

filtration area

0.5 m2

screen size

, Type C screen (coarse screen)

volume

118 mL , in feed channel
133 mL , in permeate channel

impurities

≤5 ppm Meets TOC (in retentate effluent, after a WFI flush of 20 L/m2)

matrix

Ultracel®

pore size

100 kDa

pH range

2-13

Quality Level

400

fitting

inlet/outlet connection (Feed: 3/4" Sanitary Flange)
 inlet/outlet connection (Permeate: 3/4" Sanitary Flange)
 inlet/outlet connection (Retentate: 3/4" Sanitary Flange)

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Application

Viral Gene Therapies, Vaccines, Concentration, Diafiltration, Buffer exchange, Protein purification, mRNA

Features and Benefits

Plug ′n play, holderless design - easy to install, safe to remove
Gamma sterilized and preservative-free - ready to process in minutes
True single-use, self-contained capsule - fast, safe, and flexible batch turnaround
Proven Ultracel® membrane and C screen - high recovery, superior mass transfer, solvent resistance
Pellicon® TFF proven performance - true linear scalability within Pellicon® TFF families

General description

The Pellicon® Capsule is the first of its kind -- a true single-use TFF device that comes ready to process in minutes. Self-contained, it employs an easy-to-use, holderless format and is supplied sterilized by irradiation.

Other Notes

The Emprove® Program complements the product portfolio through

Comprehensive documentation to support qualification, risk assessment and process optimization needs.
Consolidation of product specific testing, quality and regulatory information to simplify compliance requirements.
Convenient 24/7 access to up-to-date product information.

Packaging

A foam clamshell is inserted over the end caps on both ends of the capsule which is then double-bagged and vacuum sealed. The double-bagged capsule is placed on a tray and then individually boxed.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
Pellicon is a registered trademark of Merck KGaA, Darmstadt, Germany
ULTRACEL is a registered trademark of Merck KGaA, Darmstadt, Germany

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商品

Scalable Tangential Flow Filtration (TFF) for Downstream Processing of Viral Vectors for Gene Therapy and Vaccine Production

Our overview of scalable tangential flow filtration for viral vector production will provide key considerations for developing and optimizing your downstream process.

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