切向流过滤设备
从一次性到可复用性产品,我们的切向流过滤 (TFF) 产品是制药和生物制药制造的理想选择。
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Pellicon® 单程TFF
单程 TFF 配备我们的Pellicon® 囊式和盒式过滤器,通过浓缩工艺物流简化加工,无需传统TFE的再循环。这是一种增加产能、浓度和产品回收率同时改进占地面积的简单方法。在结合了在线减少体积与其它工艺步骤的过程中,这种多功能应用还可以实现连续和强化的处理。
Pellicon® 囊式过滤器
Pellicon® 囊式过滤器配备Ultracel® 滤膜,设计用于简化生物制药的超滤和渗滤,提供易用性和工艺灵活性。这种创新的囊式过滤器是真正的一次性 TFF 设备,具有独特的即插即用、无支架设计,可在几分钟内完成处理准备。
Pellicon® 3盒式过滤器
Pellicon® 3盒式过滤器 提供高蛋白质产率和一致的性能,同时提供广泛的化学相容性。它们可与 Ultracel® 和Biomax® 滤膜一起提供,用于不同的加工需求,包括单克隆抗体、血浆、胰岛素、肽和疫苗。为了克服高粘度挑战,我们配备 D滤网的Pellicon® 3 盒式过滤器经过优化,可实现更高的蛋白质浓度。
Pellicon® 2 盒式过滤器
Pellicon® 2 盒式过滤器 是生物制剂超滤和渗滤的理想选择,包括多糖、病毒悬浮液和蛋白质溶液的浓缩、脱盐和缓冲液交换。我们的Ultracel® 和 Biomax® 滤膜提供高效的超滤过程,而 Durapore® 滤膜最适合微滤。
Pellicon® XL 50 盒式过滤器
Pellicon® XL 50 盒式过滤器可配合我们的超滤和微滤膜使用,为工艺开发或小体积处理带来线性可扩展性。
Prostak™ 微滤模块
Prostak™微滤模块 提供坚固的结构、可靠的性能和在线蒸汽灭菌能力,适用于澄清、细胞收获和多用途灌注。低滞留体积和开放的通道设计为剪切敏感型材料的处理实现了高产品回收率和温和的流动路径。
有助于您开展资质认证、风险评估和工艺优化
为和我们的产品线互为补充,Emprove®计划提供了三种类型的档案,可针对开发和制造运行各环节提供全程支持,包括认证、风险评估和工艺优化环节。这些档案以易于使用的格式对特定于产品的全面测试数据、质量声明和法规信息进行了合并,以简化您的合规性需求。
相关文章
- Tangential Flow Filtration in Downstream Bioprocessing
There are many options for tangential flow filtration (TFF) in downstream bioprocessing from multi-use to single-use TFF or batch TFF and single-pass TFF.
- Tangential Flow Filtration in the Antibody Drug Conjugate (ADC) Manufacturing Process
Find best practices for using Pellicon® Capsules in ADC processing as well as data from two studies using Pellicon® Capsules and Pellicon® cassettes in the ADC manufacturing process.
- Single-Pass Tangential Flow Filtration Implementation and Scaling
Get practical guidance on using single-pass tangential flow filtration in your downstream process and scaling between capsules and cassettes.
相关产品资源
- Data Sheet: Pellicon® Capsules with Ultracel® Membrane
Accelerate your therapy using our innovative single-use tangential flow filters with superior flux performance
- Data Sheet: Pellicon® 3 Cassettes with Ultracel® Membrane
The optimum tangential flow filtration devices for monoclonal antibodies and other therapeutic proteins.
- Data Sheet: Pellicon® 3 Cassettes with Biomax® Membrane
The device of choice for applications requiring higher yield, fast processing, and exceptional chemical resistance
- Data Sheet: Pellicon® 2 Filters and Holders
High performance tangential flow filters for biopharmaceutical process development, scale-up and scale-down, concentration, purification, and cell harvesting applications.
- Data Sheet: Prostak™ Microfiltration Modules
Prostak™ modules are tangential flow stacked plate membrane devices with open feed channels, made for use in Prostak™ tangential flow filtration (TFF) systems.
- Data Sheet: Pellicon® XL 50 Cassettes
Easy-to-use, high performance, linearly scalable tangential flow filtration cassette for process development work at volumes from 50 to 1000 mL
- Data Sheet: Pellicon® Single-Pass Tangential Flow Filtration
Pellicon® single-pass tangential flow filtration (single-pass TFF) is a versatile technology for more productive, high capacity and cost effective downstream processes that allows facilities to meet the demands of higher titer and connected or continuous processes
- Data Sheet: Ultracel® Membranes
The membrane of choice for ultra-low protein binding and robust performance during concentration and diafiltration of therapeutics
- Data Sheet: Biomax® Membranes
The membrane of choice for fast processing and exceptional chemical resistance
- Performance Guide: Pellicon® Capsules with Ultracel® Membrane
Innovative, high performance single-use tangential flow filtration devices that offer ease-of-use, operational flexibility, and enhanced operator safety.
- Application Note: Pellicon® Capsules for Single-use Tangential Flow Filtration
The Pellicon® Capsule is the first of its kind—a true single-use TFF device that streamlines bioprocessing with its innovative, simplified design and user-friendly features.
- Performance Guide: Pellicon® 3 Cassettes with Ultracel® Membrane
The tangential flow filtration devices of choice for demanding filtration processes requiring unbeatable performance consistency.
- Performance Guide: Pellicon® 3 Cassettes with Biomax® Membrane
The tangential flow filtration device of choice for demanding filtration processes requiring unbeatable performance consistency
- Application Note: Pellicon® 3 Cassettes with High Viscosity Feed Screen
Pellicon® 3 Cassettes with Ultracel® and Biomax® 30kD Membrane utilizing D screen geometry are engineered to efficiently process higher viscosity products.
- Application Note: Process Optimization and Scalability Evaluation of Pellicon® Capsules for Single-pass Tangential Flow Filtration of mAb-Based Biomolecules
Single-pass tangential flow filtration (SPTFF) is a method of ultrafiltration for the purposes of either volume reduction or protein concentration.
- White Paper: Streamlining Bioprocessing Using Pellicon® Cassettes for Single-pass Operation
Single-pass TFF is an enhanced approach to the existing TFF technology that has been used for the purification of monoclonal antibodies, therapeutic proteins, and vaccines at different steps within downstream processing
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