产品名称
Multiscreen® 96孔板，聚碳酸酯膜, pore size 0.45 μm, non-sterile
description
This 96-well filter plate has a Polycarbonate membrane used for Permeability studies.
sterility
non-sterile
Quality Level
material
clear polystyrene plate
flat bottom wells
polycarbonate membrane
usage
Manual
feature
hydrophilic
lid
packaging
pkg of 10 plates
manufacturer/tradename
MultiScreen®
technique(s)
DNA purification: suitable
activity assay: suitable (with precipitations)
ligand binding assay: suitable
parallel artificial membrane permeation assay (PAMPA): suitable
receptor binding assay: suitable
plate size
96 wells
well maximum volume
300 μL
working volume
50-250 μL
pore size
0.45 μm pore size
application(s)
sample preparation
compatibility
manifold only
shipped in
ambient
Application
测定
蛋白质
General description
MultiScreen Permeability、MultiScreen-IP和MultiScreen Acceptor板支持用于预测被动转运的人工膜策略。
膜具有均匀的孔结构和密度以实现可靠的转运:
- 单个孔最小化候选串扰
- 与自动液体处理系统的兼容性增加了通量
渗透性测定：
- MultiScreen渗透板具有聚碳酸酯膜，可支持用于渗透试验的己烷/十六烷人工层。1
PAMPA测定：
- MultiScreen-IP板具有疏水性PVDF膜，支持PAMPA ASAys的脂质双层。2,3
MultiScreen Acceptor板：
- MultiScreen Acceptor板可以与任一板一起使用，以捕获被动转运的化合物。该板由100% PTFE构成，根据所评估的小分子的电荷，可以改善LC/MS结果。
Other Notes
Physical form
Legal Information
商品
Combining solubility & PAMPA assays streamlines drug permeability testing.
This is a white paper on the Evaluation of the reproducibility of Parallel Artificial Membrane Permeation Assays (PAMPA) using MultiScreen® Filter Plates.
This is a protocol for a Membrane Integrity test for Lipid-PAMPA Artificial Membranes
实验方案
Assays that predict passive absorption of orally administered drugs have become increasingly important in the drug discovery process. As previously described by Faller and Kansy such assays provide rapid, low cost and automation friendly methods to measure a compound’s passive permeability.
相关内容
成功筛选药物靶点和先导化合物发现需要经过检验、专用于特定工艺的高通量试剂和用品。查找适合您的CRO、制药或生物技术工艺的工具，进行小分子和生物药物筛选并以及稳定的药物安全性免疫原性检测。
High-throughput reagents for drug target screening and immunogenicity testing.
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