物料
PVDF membrane (hydrophobic)
acrylic
flat bottom wells
质量水平
描述
Non-sterile, clear 96-well filter plate with 0.45 um pore size Hydrophobic PVDF membrane for Avidin-biotin Linkages, DNA-binding Proteins, Protein Binding & PAMPA. Comes in a pack of 50.
无菌性
non-sterile
产品线
MultiScreen®
特点
hydrophobic
lid
制造商/商品名称
MultiScreen®
参数
50-250 μL sample volume (per well)
技术
parallel artificial membrane permeation assay (PAMPA): suitable
过滤面积
0.3 cm2
板尺寸
96 wells
孔最大体积
300 μL
工作体积
50-250 μL
基质
Immobilon®-P
孔径
0.45 μm pore size
吸附类型
high binding surface
运输
ambient
相关类别
应用
- 在平行人工膜渗透试验(PAMPA)中用作人工膜支撑和接收板,以测定肟的渗透性
- 酶联免疫斑点(ELISpot)检测
- 钥孔戚血蓝素(KLH)特异性ELISPOT,用于抗原(Ag)特异性细胞的鉴定
法律信息
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商品
This is a white paper on the Evaluation of the reproducibility of Parallel Artificial Membrane Permeation Assays (PAMPA) using MultiScreen® Filter Plates.
This is a protocol for a Membrane Integrity test for Lipid-PAMPA Artificial Membranes
Combining solubility & PAMPA assays streamlines drug permeability testing.
实验方案
Assays that predict passive absorption of orally administered drugs have become increasingly important in the drug discovery process. As previously described by Faller and Kansy such assays provide rapid, low cost and automation friendly methods to measure a compound’s passive permeability.
Guidelines for various bioassays on the MultiScreen system, which makes it possible to carry out an assay from sample incubation to scintillation counting in a 96-well plate.
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