MABS276
抗-pan聚甘氨酸化微管蛋白抗体，克隆AXO 49
clone AXO 49, from mouse
登录 查看组织和合同定价。
选择尺寸
变更视图
关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Clone:
AXO 49, monoclonal
Species reactivity:
Apis, porcine, snail, pig, sea urchin, protista, sheep, mouse, lemur, Drosophila, Paramecium, trout
Application:
DB, IF, WB
Citations:
17
biological source
mouse
Quality Level
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
AXO 49, monoclonal
species reactivity
Apis, porcine, snail, pig, sea urchin, protista, sheep, mouse, lemur, Drosophila, Paramecium, trout
should not react with
Euglena, human (cilia)
technique(s)
dot blot: suitable, immunofluorescence: suitable, western blot: suitable
isotype
IgG1κ
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... TUBA1A(7846)
General description
已经在真核细胞中鉴定了微管蛋白的几种翻译后修饰。 糖基化是一种多修饰，其发生在纤毛草履虫的轴丝微管蛋白中鉴定的可变长度的甘氨酸链的侧向分支中。已经在许多单细胞和多细胞生物的微管蛋白和/或纤毛/鞭毛上检测到这种修饰。细胞质和轴丝室之间不同的聚糖基化微管蛋白亚型的差异分布表明，微管蛋白的聚糖基化水平在细胞水平上受到高度调节。AXO49抗体主要对运动性纤毛和鞭毛的轴丝微管蛋白具有反应性，这些纤毛和鞭毛被聚甘氨酰化。在某些情况下，还可以在其他非常稳定的微管网络上观察到反应性。该抗体可用于纤毛和鞭毛检测。
观测分子量〜55 kDa
Immunogen
草履虫纤毛（草履虫轴丝）的不溶性部分
Application
使用该小鼠单克隆抗体（抗泛聚甘氨酰化微管蛋白抗体，克隆AXO 49，经验证可用于蛋白质印迹和免疫荧光&斑点印迹）检测微管蛋白。
Biochem/physiol Actions
该抗体可识别含有至少3个甘氨酸残基的聚合物的侧向连接分支。该抗体与聚甘氨酰化微管蛋白以及其他聚甘氨酰化蛋白具有交叉反应性。
Physical form
形式：纯化
Analysis Note
通过蛋白质印迹法评估草履虫的总细胞骨架蛋白。：该抗体以1:50,000稀释度在10 µg草履虫总细胞骨架蛋白中检测到聚糖基化微管蛋白。
Other Notes
浓度：关于批次特定浓度请参见检验报告。
Still not finding the right product?
试用我们的 产品选型工具 工具缩小选择范围
存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Harrison D Pravder et al.
International journal of molecular sciences, 23(6) (2022-03-26)
A useful model for determining the mechanisms by which actin and actin binding proteins control cellular architecture is the Drosophila melanogaster process of spermatogenesis. During the final step of spermatogenesis, 64 syncytial spermatids individualized as stable actin cones move synchronously
Suzanne H Hodge et al.
Biology open, 10(8) (2021-08-07)
Primary cilia are compartmentalised from the rest of the cell by a ciliary gate comprising transition fibres and a transition zone. The ciliary gate allows the selective import and export of molecules such as transmembrane receptors and transport proteins. These
Sai Aung Phyo et al.
Frontiers in cell and developmental biology, 10, 837486-837486 (2022-04-19)
A proliferated and post-translationally modified microtubule network underlies cellular growth in cardiac hypertrophy and contributes to contractile dysfunction in heart failure. Yet how the heart achieves this modified network is poorly understood. Determining how the "tubulin code"-the permutations of tubulin
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| MABS276 | 04053252927997 |