Anti-phospho STAT6 (Tyr641) Antibody, clone 19E2.1

Signal transducer and activator of transcription 6 (STAT6) transduces signals from extracellular cytokines during adaptive immunity and has recently been found to be important in the innate immune response to viral infection. STAT6 is also involved in the attenuation of the Th1 and Th17 in the nephritogenic immune response. The consequence of STAT6 activity has been associated with the pathogenesis of autoimmune disease and has been found to be actively imported to the nucleus.

This antibody recognizes STAT6 phosphorylated at (Tyr641).

Epitope: Phosphorylated (Tyr641)

KLH-conjugated linear peptide corresponding to human STAT6 phosphorylated at (Tyr641).

Anti-phospho STAT6 (Tyr641) Antibody, clone 19E2.1 is a mouse monoclonal antibody for detection of phospho STAT6 (Tyr641) also known as Signal transducer & activator of transcription 6, IL-4 Stat & has been validated in WB, FC.

Flow Cytometry Analysis: 2 µg/mL from a representative lot detected STAT6 in human peripheral blood leukocytes.

Research Category
Epigenetics & Nuclear Function

Research Sub Category
Transcription Factors

Evaluated by Western Blot in NIH/3T3 cell lysates treated and untreated with PDGF.

Western Blot Analysis: 0.5 µg/mL of this antibody detected STAT6 on 10 µg of PDGF untreated and treated NIH/3T3 cell lysates.

~165 kDa observed

Protein G Purified

Format: Purified

Purified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Stable for 1 year at 2-8°C from date of receipt.

Control
NIH/3T3 cell lysates treated and untreated with PDGF

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

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