STAT6
signal transducer and activator of transcription 6, interleukin-4 induced
别名:
D12S1644, IL-4-STAT, STAT6B, STAT6C
物种:
Human STAT6 (6778), Mouse Stat6 (20852), Rat Stat6 (362896), domestic cat STAT6 (101089873), chicken STAT6 (100859196), dog STAT6 (100142679), sheep STAT6 (101102134), cow STAT6 (353105), Horse STAT6 (100050053), Zebrafish stat6 (337413) ...展开
UniProtKB ID:
基因ID:
- Human(6778) Summary: The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
- Mouse(20852) signal transducer and activator of transcription 6
- Rat(362896) signal transducer and activator of transcription 6, interleukin-4 induced
- domestic cat(101089873) signal transducer and activator of transcription 6, interleukin-4 induced
- chicken(100859196) signal transducer and activator of transcription 6, interleukin-4 induced
- dog(100142679) signal transducer and activator of transcription 6, interleukin-4 induced
- sheep(101102134) signal transducer and activator of transcription 6, interleukin-4 induced
- cow(353105) signal transducer and activator of transcription 6, interleukin-4 induced
- Horse(100050053) signal transducer and activator of transcription 6, interleukin-4 induced
- Zebrafish(337413) signal transducer and activator of transcription 6, interleukin-4 induced
- domestic guinea pig(100726686) signal transducer and activator of transcription 6, interleukin-4 induced
- naked mole-rat(101725744) signal transducer and activator of transcription 6, interleukin-4 induced
- Domestic Rabbit(100344264) signal transducer and activator of transcription 6, interleukin-4 induced
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ELISA
Antibodies
货号
说明
物种反应性
应用
Anti-STAT6 antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-STAT6 Antibody, clone 1C13 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
human, monkey
应用
affinity binding assay
flow cytometry
immunohistochemistry
western blot
flow cytometry
immunohistochemistry
western blot
Anti-phospho-STAT6 (pTyr641) antibody produced in rabbit, affinity isolated antibody,
物种反应性
human
应用
immunohistochemistry
western blot
western blot
Anti-phospho STAT6 (Tyr641) Antibody, clone 19E2.1, clone 19E2.1, from mouse,
物种反应性
human, mouse
应用
flow cytometry
western blot
western blot
Proteins
货号
说明
物种
STAT6, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
human