推荐产品
生物来源
mouse
质量水平
抗体形式
ascites fluid
抗体产品类型
primary antibodies
克隆
monoclonal
种属反应性（根据同源性预测）
mammals
制造商/商品名称
Chemicon®
技术
western blot: suitable
同位素/亚型
IgG2a
NCBI登记号
UniProt登记号
运输
dry ice
靶向翻译后修饰
unmodified
基因信息
human ... TUBA1A(7846)
特异性
Alpha tubulin, detyrosinated.
免疫原
Epitope: detyrosinated
Synthetic peptide GEEEGE.
应用
(add note)
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neurofilament & Neuron Metabolism
Neuronal & Glial Markers
Neurofilament & Neuron Metabolism
Neuronal & Glial Markers
This Anti-Tubulin Antibody, α, detyrosinated is validated for use in WB for the detection of Tubulin.
外形
Liquid. Contains no preservative.
储存及稳定性
Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
10 - Combustible liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Low-intensity pulsed ultrasound accelerates tooth movement via activation of the BMP-2 signaling pathway.
Xue, H; Zheng, J; Cui, Z; Bai, X; Li, G; Zhang, C; He, S; Li, W; Lajud, SA; Duan, Y; Zhou, H
Testing null
Yu-Ming Lu et al.
eLife, 13 (2024-07-01)
Tubulin posttranslational modifications (PTMs) modulate the dynamic properties of microtubules and their interactions with other proteins. However, the effects of tubulin PTMs were often revealed indirectly through the deletion of modifying enzymes or the overexpression of tubulin mutants. In this
Fan Zhang et al.
Translational neurodegeneration, 4, 9-9 (2015-06-02)
In Alzheimer disease (AD), hyperphosphorylation of tau proteins results in microtubule destabilization and cytoskeletal abnormalities. Our prior ultra-morphometric studies documented a clear reduction in microtubules in pyramidal neurons in AD compared to controls, however, this reduction did not coincide with
Leticia Peris et al.
Brain : a journal of neurology (2022-02-12)
Microtubules play fundamental roles in the maintenance of neuronal processes and in synaptic function and plasticity. While dynamic microtubules are mainly composed of tyrosinated tubulin, long-lived microtubules contain detyrosinated tubulin, suggesting that the tubulin tyrosination/detyrosination cycle is a key player
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International journal of molecular sciences, 22(11) (2021-07-03)
During aggressive cancer progression, cancer cells adapt to unique microenvironments by withstanding various cellular stresses, including endoplasmic reticulum (ER) stress. However, the mechanism whereby cancer cells overcome the ER stress to survive remains to be elucidated. Herein, we demonstrated that
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