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Merck
CN

MAB1953

Anti-Integrin αV (ITGAV/CD51) Antibody

CHEMICON®, mouse monoclonal, P3G8

别名:

CD51

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关于此项目

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
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产品名称

Anti-Integrin αV Antibody, clone P3G8, clone P3G8, Chemicon®, from mouse

biological source

mouse

antibody form

purified antibody

antibody product type

primary antibodies

clone

P3G8, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
flow cytometry: suitable
immunocytochemistry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable

isotype

IgG1

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

Gene Information

human ... ITGAV(3685)

Immunogen

UCLA P3 lung carcinoma cells

Application

Research Sub Category
Integrins
Anti-Integrin αV Antibody, clone P3G8 is an antibody against Integrin αV for use in ELISA, FC, IP, IC, IH.
Immunohistochemistry: 1:1,000. For use on acetone or paraformaldehyde fixed tissue

Immunocytochemistry: 1:1,000. Will react with some lymphoid cell lines (B cells), many carcinoma and melanoma cell lines and osteosarcomas.

Flow cytometry

Immunoprecipitation

FACS

EIA

Optimal working dilutions must be determined by end user.
Research Category
Cell Structure

Biochem/physiol Actions

Reacts with human alphaV integrin subunit and with all alphaV-containing integrin receptors.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Format: Purified

Preparation Note

Maintain at 2-8°C in undiluted aliquots for up to 6 months.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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存储类别

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


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Maria Rita Milone et al.
Oncotarget, 6(7), 5324-5341 (2014-12-08)
Proteomic analysis identified differentially expressed proteins between zoledronic acid-resistant and aggressive DU145R80 prostate cancer (PCa) cells and their parental DU145 cells. Ingenuity Pathway Analysis (IPA) showed a strong relationship between the identified proteins within a network associated with cancer and
Keijiro Ishikawa et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 28(1), 131-142 (2013-09-12)
Proliferative vitreoretinopathy (PVR) is a severe, vision-threatening disorder characterized by the fibrous membrane formation that leads to tractional retinal detachment. There has been no effective therapeutic approach other than vitreoretinal surgery. In this study, DNA microarray analysis of the fibrous
Mannose 6-phosphate/insulin-like growth factor 2 receptor limits cell invasion by controlling alphaVbeta3 integrin expression and proteolytic processing of urokinase-type plasminogen activator receptor.
Schiller, HB; Szekeres, A; Binder, BR; Stockinger, H; Leksa, V
Molecular Biology of the Cell null
D H Chai et al.
Osteoarthritis and cartilage, 18(2), 249-256 (2009-10-06)
Our goal was to test the hypothesis that specific integrin receptors regulate chondrocyte biosynthetic response to dynamic compression at early times in 3D gel culture, during initial evolution of the pericellular matrix, but prior to significant accumulation of further-removed matrix.
Tropism-modified AAV vectors overcome barriers to successful cutaneous therapy.
Sallach, J; Di Pasquale, G; Larcher, F; Niehoff, N; Rubsam, M; Huber, A; Chiorini et al.
Molecular Therapy null

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