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Merck
CN

ITGAV

integrin, alpha V

别名:
CD51, MSK8, VNRA, VTNR
物种:
UniProtKB ID:
基因ID:
  • Human(3685) Summary: This gene encodes a protein that is a member of the integrin superfamily. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein undergoes post-translational cleavage to yield disulfide-linked heavy and light chains that combine with multiple integrin beta chains to form different integrins. This protein has been shown to heterodimerize with beta 1, beta 3, beta 5, beta 6, and beta 8; the heterodimer of alpha v and beta 3 is the Vitronectin receptor. This protein interacts with several extracellular matrix proteins to mediate cell adhesion and may play a role in cell migration. It is proposed that this protein may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, May 2013]
  • Mouse(16410) integrin alpha V
  • Rat(296456) integrin, alpha V
  • dog(488437) integrin, alpha V
  • naked mole-rat(101717672) integrin, alpha V
  • domestic guinea pig(100728575) integrin, alpha V
  • domestic cat(101085820) integrin, alpha V
  • chicken(396420) integrin, alpha V
  • Zebrafish(100151255) integrin, alpha V
  • Domestic Rabbit(100008956) integrin, alpha V
  • cow(281875) integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)
  • sheep(443143) integrin, alpha V
  • Horse(100068706) integrin, alpha V

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Small Molecule - Antagonist

货号
说明
物种
Gly-Arg-Gly-Asp-Ser-Pro-Lys, ≥97% (HPLC),
物种
human

Antibodies

货号
说明
物种反应性
应用
抗整合素αVβ 6抗体,克隆10D5,无叠氮化物, clone 10D5, Chemicon®, from mouse,
物种反应性
human, mouse, rat
应用
flow cytometry
immunoprecipitation (IP)
抗整合素αVβ3抗体,克隆LM609, clone LM609, Chemicon®, from mouse,
物种反应性
avian, bovine, canine, chicken, human, monkey, pig, rabbit
应用
flow cytometry
immunofluorescence

immunohistochemistry

immunoprecipitation (IP)
Anti-Integrin αV Antibody, clone LM142, ,
物种反应性
human
应用
flow cytometry
immunofluorescence

immunohistochemistry

neutralization
抗整合素αV抗体(克隆LM142), ascites fluid, clone LM142, Chemicon®,
物种反应性
human
应用
immunohistochemistry
immunoprecipitation (IP)
抗整合素 αVβ5抗体,克隆P1F6, clone P1F6, Chemicon®, from mouse,
物种反应性
chicken, human
应用
flow cytometry
immunocytochemistry

immunohistochemistry

immunoprecipitation (IP)

Proteins

货号
说明
物种
人整合素αVβ3,辛基-β-D-吡喃葡萄糖苷处方, ,
物种
human
Human Integrin αVβ3 Protein, Triton X-100 Formulation, ,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting mouse Itgav,
物种
mouse
MISSION® esiRNA, targeting human ITGAV,
物种
human