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Merck
CN

HCDC0001L0100

Millipore

Mobius Gold High Cell Density Cryopreservation Assembly

(-196C), 100 mL, sterile; y-irradiated (at 25-40 kGy)

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About This Item

UNSPSC代码:
41103801

物料

(flouropolymer)
(thermoplastic elastomer)
device
polypropylene
silicone (thermoplastic elastomer)

质量水平

Agency

according to ISO 11137
meets EN 2.6.14
meets JP 4.01
meets USP 85

无菌性

sterile; γ-irradiated (at 25-40 kGy)

参数

-196- 60 °C temp. range (-321- 140 °F)
0.3 bar max. pressure (4.4 psi)
60 mL process volume

容量

100 mL

杂质

<0.25 EU/mL Aqueous extraction (LAL test)

应用

mAb

储存温度

2-30°C

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一般描述

Device configuration: 5 bags per assembly
Our Mobius® High Cell Density Cryopreservation (HCDC) Assembly (-196C) is a single-use assembly specially designed to facilitate the freeze and thaw of cryopreserved cells in liquid nitrogen vapor phase (? -196°C). Available in two assembly bag sizes of 100 mL and 250 mL, our Mobius® HCDC Assembly (-196C) enables seed train inoculation with cells at a higher cell density and larger volume compared to the traditional seed train process using vials, which significantly accelerates the cell expansion process. Our Mobius® single-use assembly also provides a closed processing environment preventing contamination while improving process reproducibility.

特异性

All component materials, in contact with sampling liquid, meet the criteria for Class VI testing based on USP <88> Biological Reactivity, in vivo.
Application

应用

Croyopreserved storage of cells

包装

Five (5) assembies per package with each assembly containing five (5) 100 mL cryo bags

组分

Fluoropolymer bags: Tubing: Silicone and Thermoplastic ElastomerFittings: PolypropyleneNovaSeal Pinch Pipes: Nickel plated brass
Pinch clamp: Nylon

其他说明

Bags manufactured under ISO Clean Room Class 8 conditions in a facility certified to ISO 14644-1 standards. Assembly performed under ISO Clean Room Class 7 conditions in a facility certified to ISO 14644-1 standards.

法律信息

MOBIUS is a registered trademark of Merck KGaA, Darmstadt, Germany

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This page describes the design attributes of the Cellicon® filter assembly for cell retention and how they simplify scale-up of intensified upstream processes.

High cell density cryopreservation (HCDC) is a closed processing alternative to the traditional seed train expansion process. Learn more about the benefits of HCDC.

How the Cellicon® filter and controller enables seamless adoption of a perfused N-1 seed train step into the cell expansion process.

Cellvento 4CHO-X Expansion Medium enhances cell biomass for bioreactor inoculation in cell expansion stages.

相关内容

生物制药开发商需要高效、高产的上游工艺来提供优质的单克隆抗体(mAb)和其他类型重组蛋白。工艺强化可确保生产策略适应未来发展需求、降低成本并提升设施灵活性。

Biopharmaceutical developers need efficient, productive upstream processes that deliver high quality monoclonal antibodies (mAbs) and other types of recombinant proteins. Process intensification can future-proof their manufacturing strategies, reduce costs, and increase facility flexibility.

生物制药开发商需要高效、高产的上游工艺来提供优质的单克隆抗体(mAb)和其他类型重组蛋白。工艺强化可确保生产策略适应未来发展需求、降低成本并提升设施灵活性。

Biopharmaceutical developers need efficient, productive upstream processes that deliver high quality monoclonal antibodies (mAbs) and other types of recombinant proteins. Process intensification can future-proof their manufacturing strategies, reduce costs, and increase facility flexibility.

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