Goat Anti-Mouse IgM+IgG+IgA Antibody, F(ab′)2, Species Adsorbed

IgG is the most abundant immunoglobulin comprising two heavy chains and two light chains. Each molecule has two antigen binding sites. IgG has 4 subclasses: IgG1 (66%), IgG2 (23%), IgG3 (7%) and IgG4 (4%). IgM constitutes about 10% of serum immunoglobulins. IgM (with IgD) is the major immunoglobulin expressed on the surface of B cells. Monomeric IgA constitutes 5-15 % of the serum immunoglobulins whereas dimeric IgA is localized to mucosa surfaces.

Reacts with heavy and light chains of mouse IgM, IgG1, IgG2a, IgG2b, IgG3 and IgA. Absorbed for human sera and purified human paraproteins. Minimal cross reactivity with human immunoglobulins.

The antibody reacts with the heavy and light chains of mouse IgM, IgG1, IgG2a, IgG2b, IgG3 and IgA as demonstrated by ELISA and flow cytometry. Minimal cross reactivity with human immunoglobulins.

Epitope: Mouse IgM, IgG, IgA

Prepared from pepsin digest of mouse Ig (H+L).

Goat anti-Mouse IgM+IgG+IgA Antibody, F(ab′)2, Species Adsorbed is an antibody against Mouse IgM+IgG+IgA for use in ELISA.

Research Category
Secondary & Control Antibodies

Research Sub Category
Fragment Specific Secondary Antibodies

Gel filtration chromatography

Purified by gel filtration chromatography of pepsin digested antibody. Liquid in 1.0 mL of 100 mM borate buffered saline, pH 8.2.

Maintain refrigerated at 2°-8°C under sterile conditions for up to twelve months from date of receipt.

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