产品名称
山羊抗人IgM抗体，Fc5µ，HRP偶联, Chemicon®, from goat
biological source
goat
conjugate
peroxidase conjugate
antibody form
affinity isolated antibody
antibody product type
secondary antibodies
clone
polyclonal
species reactivity
human
manufacturer/tradename
Chemicon®
technique(s)
ELISA: suitable
western blot: suitable
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Application
EIA：1：5,000-1：100,000。
蛋白质印迹：1：5,000-1：200,000。
免疫组化：1：500-1：5,000。
最佳工作稀释度必须由最终用户进行确定。
蛋白质印迹：1：5,000-1：200,000。
免疫组化：1：500-1：5,000。
最佳工作稀释度必须由最终用户进行确定。
山羊抗人IgM抗体，Fc5μ，HRP偶联物是一种抗人IgM的抗体，用于ELISA &WB。
研究子类别
片段特异性二抗
片段特异性二抗
研究类别
二抗&对照抗体
二抗&对照抗体
Biochem/physiol Actions
基于免疫电泳，该抗体可与人IgM重链的Fc5μ部分反应。不与人IgG或IgA或人免疫球蛋白的轻链反应。对非免疫球蛋白血清蛋白无反应性，但该抗体可能与其他种属的IgM发生交叉反应。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
IgM约占血清免疫球蛋白的10%。IgM在对大多数抗原的早期免疫反应中是突出的，并且在某些抗体反应（例如′天然′血型抗体）中占主导地位。IgM（含IgD）是B细胞表面表达的主要免疫球蛋白。
Immunogen
采用纯化的人IgM Fc5μ片段制备。
Physical form
0.01 M磷酸钠，0.25 M NaCl，pH值7.6，含15mg/ml BSA。不含防腐剂。冻干。
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Cleopatra K Mugyenyi et al.
PloS one, 8(7), e68304-e68304 (2013-07-19)
Antibodies to P. falciparum apical membrane protein 1 (AMA1) may contribute to protective immunity against clinical malaria by inhibiting blood stage growth of P. falciparum, and AMA1 is a leading malaria vaccine candidate. Currently, there is limited knowledge of the
Sanne Reijm et al.
Arthritis research & therapy, 23(1), 230-230 (2021-09-05)
Anti-modified protein antibodies (AMPA) targeting citrullinated, acetylated and/or carbamylated self-antigens are hallmarks of rheumatoid arthritis (RA). Although AMPA-IgG cross-reactivity to multiple post-translational modifications (PTMs) is evident, it is unknown whether the first responding B cells, expressing IgM, display similar characteristics
Lin Sun et al.
Frontiers in bioengineering and biotechnology, 11, 1320586-1320586 (2023-12-21)
Plants are being increasingly recognized for the production of complex human proteins, including monoclonal antibodies (mAbs). Various methods have been applied to boost recombinant expression, with DNA codon usage being an important approach. Here, we transiently expressed three complex human
Juan Rivera-Correa et al.
eLife, 8 (2019-11-13)
Anemia is a common complication of malaria that is characterized by the loss of infected and uninfected erythrocytes. In mouse malaria models, clearance of uninfected erythrocytes is promoted by autoimmune anti-phosphatidylserine (PS) antibodies produced by T-bet+B-cells, which bind to exposed
Baoqing Sun et al.
Emerging microbes & infections, 9(1), 940-948 (2020-05-03)
The emerging COVID-19 caused by SARS-CoV-2 infection poses severe challenges to global public health. Serum antibody testing is becoming one of the critical methods for the diagnosis of COVID-19 patients. We investigated IgM and IgG responses against SARS-CoV-2 nucleocapsid (N)
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