推荐产品
生物来源
goat
质量水平
偶联物
peroxidase conjugate
抗体形式
F(ab′)2 fragment of affinity isolated antibody
抗体产品类型
secondary antibodies
克隆
polyclonal
种属反应性
human
制造商/商品名称
Chemicon®
技术
ELISA: suitable
western blot: suitable
运输
wet ice
靶向翻译后修饰
unmodified
一般描述
免疫球蛋白G（IgG）是在人血清中发现的最常见的抗体同型。它以IgG1、IgG2、IgG3和IgG4四种亚型存在。IgG结构包含四条多肽链，由两条相同的重（H）链和两条相同的λ轻（L）链组成。这些链通过二硫键相互连接。IgG由B细胞产生。
免疫原
人 IgG
应用
羊抗人IgG抗体Fc，HRP偶联物已用于酶联免疫吸附试验（ELISA）（1:3,000）。
还可用于：
还可用于：
- 酶免疫测试（EIA），OPD：1:5,000-1:100,000
- 免疫组织化学1:500-1:5,000
- 蛋白质印迹
生化/生理作用
免疫球蛋白G（IgG）与抗体依赖性细胞介导的细胞毒性（ADCC）有关。它有助于激活补体系统的经典途径。它中和病毒颗粒和毒素。 母体IgG通过胎盘传递给胎儿，这对保护新生儿免受传染病的侵害至关重要。检测严重急性呼吸综合征冠状病毒（SARS-CoV）-2感染患者的IgG水平可作为评估2019冠状病毒（COVID19）严重程度和预后的潜在策略。
外形
冻干。缓冲液=0.01 M磷酸钠，0.25 M NaCl，pH值7.6和15 mg/ml BSA。不含防腐剂。
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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储存分类代码
11 - Combustible Solids
WGK
WGK 3
Sally Esmail et al.
Cell reports methods, 1(2), 100011-100011 (2021-07-09)
We have developed a rapid, accurate, and cost-effective serologic test for SARS-CoV-2 virus, which caused the COVID-19 pandemic, on the basis of antibody-dependent agglutination of antigen-coated latex particles. When validated using plasma samples that are positive or negative for SARS-CoV-2
Mengyan Li et al.
The Journal of clinical investigation, 131(23) (2021-10-22)
To delineate the in vivo role of different costimulatory signals in activating and expanding highly functional virus-specific cytotoxic CD8+ T cells, we designed synTacs, infusible biologics that recapitulate antigen-specific T cell activation signals delivered by antigen-presenting cells. We constructed synTacs
Tara Bancroft et al.
Cellular immunology, 304-305, 35-43 (2016-05-24)
The recent increase in cases of whooping cough among teenagers in the US suggests that the acellular Bordetella pertussis vaccine (aP) that became standard in the mid 1990s might be relatively less effective than the whole-bacteria formulation (wP) previously used
PCSK9 prosegment chimera as novel inhibitors of LDLR degradation.
Saavedra, YG; Zhang, J; Seidah, NG
Testing null
Margherita Passariello et al.
Scientific reports, 11(1), 11046-11046 (2021-05-28)
Among the therapies against the pandemic SARS-CoV-2 virus, monoclonal Antibodies (mAbs) targeting the Spike glycoprotein represent good candidates to interfere in the Spike/ACE2 interaction, preventing virus cell entry. Since anti-spike mAbs, used individually, might be unable to block the virus
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