生物来源
mouse
质量水平
抗体形式
purified antibody
抗体产品类型
primary antibodies
克隆
2G11, monoclonal
形式
liquid
包含
≤0.1% sodium azide as preservative
种属反应性
bovine, monkey, human
请勿与下列物质发生反应
hamster
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
avoid repeated freeze/thaw cycles
同位素/亚型
IgG2a
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... M6PR(4074)
相关类别
一般描述
Purified mouse monoclonal antibody. Recognizes the mannose 6-phosphate receptor protein.
Recognizes the ~300 kDa mannose 6-phosphate receptor protein.
This Anti-Mannose 6-Phosphate Receptor Mouse mAb (2G11) is validated for use in Immunoblotting, IF, IHC, IP for the detection of Mannose 6-Phosphate Receptor.
免疫原
Bovine
Epitope: within the extracelluar domain
native bovine cation independent (CI)-mannose 6-phosphate receptor
应用
Immunoblotting (1 µg/ml, non-reducing, see comments)
Immunofluorescence (see comments)
Immunohistochemistry (2-5 µg/ml)
Immunoprecipitation (see comments)
Immunofluorescence (see comments)
Immunohistochemistry (2-5 µg/ml)
Immunoprecipitation (see comments)
包装
Please refer to vial label for lot-specific concentration.
警告
Toxicity: Standard Handling (A)
外形
In PBS.
重悬
Following initial thaw, aliquot and freeze (-20°C).
其他说明
Dintzis, S., et al. 1994. J. Biol. Chem.269, 12159.
Dintzis, S., and Pfeffer, S. 1990. EMBO J.9, 77.
Dintzis, S., and Pfeffer, S. 1990. EMBO J.9, 77.
Does not detect MPR in hamster (CHO) cells. Not suitable for immunoblotting using reducing conditions. This antibody has also been reported to work for immunoprecipitation and immunofluorescence. Variables associated with assay conditions will dictate the proper working dilution.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
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WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
监管及禁止进口产品
Jennifer Hirst et al.
Human molecular genetics, 24(17), 4984-4996 (2015-06-19)
Adaptor proteins (AP 1-5) are heterotetrameric complexes that facilitate specialized cargo sorting in vesicular-mediated trafficking. Mutations in AP5Z1, encoding a subunit of the AP-5 complex, have been reported to cause hereditary spastic paraplegia (HSP), although their impact at the cellular
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