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Merck
CN

444105

Anti-Mannose 6-Phosphate Receptor Mouse mAb (2G11)

liquid, clone 2G11, Calbiochem®

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NACRES:
NA.41
UNSPSC Code:
12352203
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产品名称

Anti-Mannose 6-Phosphate Receptor Mouse mAb (2G11), liquid, clone 2G11, Calbiochem®

biological source

mouse

antibody form

purified antibody

antibody product type

primary antibodies

clone

2G11, monoclonal

form

liquid

contains

≤0.1% sodium azide as preservative

species reactivity

bovine, monkey, human

should not react with

hamster

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
avoid repeated freeze/thaw cycles

dilution

(Immunoblotting (1 µg/mL, non-reducing)
Immunofluorescence
Immunohistochemistry (2-5 µg/mL)
Immunoprecipitation )

isotype

IgG2a

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

Gene Information

human ... M6PR(4074)

相关类别

Application

Immunoblotting (1 µg/ml, non-reducing, see comments)

Immunofluorescence (see comments)

Immunohistochemistry (2-5 µg/ml)

Immunoprecipitation (see comments)

Disclaimer

Toxicity: Standard Handling (A)

General description

Purified mouse monoclonal antibody. Recognizes the mannose 6-phosphate receptor protein.
Recognizes the ~300 kDa mannose 6-phosphate receptor protein.
This Anti-Mannose 6-Phosphate Receptor Mouse mAb (2G11) is validated for use in Immunoblotting, IF, IHC, IP for the detection of Mannose 6-Phosphate Receptor.

Immunogen

Bovine
Epitope: within the extracelluar domain
native bovine cation independent (CI)-mannose 6-phosphate receptor

Other Notes

Dintzis, S., et al. 1994. J. Biol. Chem.269, 12159.
Dintzis, S., and Pfeffer, S. 1990. EMBO J.9, 77.
Does not detect MPR in hamster (CHO) cells. Not suitable for immunoblotting using reducing conditions. This antibody has also been reported to work for immunoprecipitation and immunofluorescence. Variables associated with assay conditions will dictate the proper working dilution.

Packaging

Please refer to vial label for lot-specific concentration.

Physical form

In PBS.

Preparation Note

Following initial thaw, aliquot and freeze (-20°C).

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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存储类别

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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Jennifer Hirst et al.
Human molecular genetics, 24(17), 4984-4996 (2015-06-19)
Adaptor proteins (AP 1-5) are heterotetrameric complexes that facilitate specialized cargo sorting in vesicular-mediated trafficking. Mutations in AP5Z1, encoding a subunit of the AP-5 complex, have been reported to cause hereditary spastic paraplegia (HSP), although their impact at the cellular

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