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Merck
CN
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文件

安全信息

428026

Sigma-Aldrich

Latrunculin A, Latrunculia magnifica

InSolution, ≥85%, 1 mM in DMSO, marine toxin that disrupts microfilament organization in cultured cells

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别名:
InSolution Latrunculin A, Latrunculia magnifica
经验公式(希尔记法):
C22H31NO5S
分子量:
421.55
UNSPSC代码:
12352200
NACRES:
NA.77

质量水平

检测方案

≥85% (HPLC)

形式

liquid

制造商/商品名称

Calbiochem®

储存条件

OK to freeze
desiccated (hygroscopic)
protect from light

运输

wet ice

储存温度

−20°C

一般描述

A cell-permeable marine toxin from the Red Sea sponge Latrunculia magnifica that disrupts microfilament organization in cultured cells by the formation of a 1:1 complex with monomeric G-actin (Kd = 200 nM). Also a potent inhibitor of microfilament-mediated processes in sperm, eggs, and embryos.

生化/生理作用

Cell permeable: yes
Primary Target
Inhibitor of microfilament-mediated processes in sperm, eggs, and embryos
Product does not compete with ATP.
Reversible: no

包装

Packaged under inert gas

警告

Toxicity: Harmful (C)

外形

A 1 mM (50 µg/119 µl) solution of Latrunculin A, Latrunculia magnifica Cat. No. 428021 in DMSO.

重悬

Following initial use, aliquot and freeze (-20°C).

其他说明

Ayscough, K.R., et al. 1997. J. Cell Biol.137, 399.
Spector, I., et al. 1989. Cell Motil. Cytoskeleton13, 127.
Coue, M., et al. 1987. FEBS Lett.213, 316.
Schatten, G., et al. 1986. Exp. Cell Res.166, 191.
Spector, I., et al. 1983. Science219, 493.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

WGK

WGK 1

法规信息

高风险级别生物产品--毒素类产品

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