跳转至内容
Merck
CN
所有图片(1)

主要文件

407137

Sigma-Aldrich

D-myo-Inositol 1,4,5-Trisphosphate, trisodium salt

≥95% (TLC), solid, second messenger involved in Ca2+ mobilization, Calbiochem®

别名:

D-myo-Inositol 1,4,5-Trisphosphate, Trisodium Salt, D-Ins(1,4,5)P₃, 3Na

登录查看公司和协议定价
所有图片(1)

About This Item

经验公式（希尔记法）:
C6H12O15P3 · 3Na
CAS号:
108340-81-4
分子量:
486.04
MDL编号:
MFCD00055051
UNSPSC代码:
12352211
NACRES:
NA.77

产品名称

D-myo-Inositol 1,4,5-Trisphosphate, Trisodium Salt, Sodium salt of D-Ins(1,4,5)P₃ that has similar biological properties as the lithium salt.

质量水平

100

方案

≥95% (TLC)

表单

solid

制造商/商品名称

Calbiochem®

储存条件

OK to freeze
desiccated (hygroscopic)

颜色

white

溶解性

water: 10 mg/mL

运输

ambient

储存温度

−20°C

SMILES字符串

[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[P](=O)([O-])([O-])O[C@H]1[C@@H]([C@H]([C@H]([C@H]([C@@H]1O)O[P](=O)([O-])[O-])O)O)O[P](=O)([O-])[O-]

InChI

1S/C6H15O15P3.6Na/c7-1-2(8)5(20-23(13,14)15)6(21-24(16,17)18)3(9)4(1)19-22(10,11)12;;;;;;/h1-9H,(H2,10,11,12)(H2,13,14,15)(H2,16,17,18);;;;;;/q;6*+1/p-6/t1-,2+,3+,4-,5-,6-;;;;;;/m1....../s1

InChI key

MLMBGBMAFNSCOW-PPKFVSOLSA-H

相关类别

一般描述

Sodium salt of D-Ins(1,4,5)P3 that has similar biological properties as the lithium salt (Cat. No. 407123).
Sodium salt of D-Ins(1,4,5)P3 that has similar biological properties as the lithium salt (Cat. No. 407123).

生化/生理作用

Cell permeable: no
Primary Target
Mobilization of Ca2+ from intracellular stores.
Product does not compete with ATP.
Reversible: no

警告

Toxicity: Standard Handling (A)

重悬

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

储存分类代码

11 - Combustible Solids

WGK

WGK 3

分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ （Lot或Batch）字后找到。

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

Ka-Chun Mok et al.
Clinical and translational medicine, 11(11), e578-e578 (2021-11-30)
Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels are members of the voltage-gated cation channel family known to be expressed in the heart and central nervous system. Ivabradine, a small molecule HCN channel-blocker, is FDA-approved for clinical use as a heart rate-reducing agent.
Jone Paesmans et al.
eLife, 9 (2020-12-23)
Synaptojanin1 (Synj1) is a phosphoinositide phosphatase, important in clathrin uncoating during endocytosis of presynaptic vesicles. It was identified as a potential drug target for Alzheimer's disease, Down syndrome, and TBC1D24-associated epilepsy, while also loss-of-function mutations in Synj1 are associated with

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门