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Merck
CN
所有图片(1)

主要文件

264103

Millipore

脱氧胆酸钠

ULTROL® Grade, ≥99% (TLC), detergent to solubilize membrane-bound proteins in their native state

别名:

3α,12α-二羟-5β-胆烷酸 钠盐, 去氧胆酸 钠盐, 脱氧胆酸 钠盐

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About This Item

经验公式(希尔记法):
C24H39NaO4
CAS号:
分子量:
414.55
Beilstein:
3581950
MDL编号:
UNSPSC代码:
12161902
NACRES:
NA.21

质量水平

方案

≥99% (TLC)

表单

solid

分子量

micellar avg mol wt 1200-5000
micellar wt 1200-4900

制造商/商品名称

Calbiochem®

储存条件

OK to freeze
desiccated (hygroscopic)

聚集数

3 - 12
3-12

颜色

white

pKa 

6.2

CMC

2 - 6 mM
2-6 mM (20-25°C)

HLB

16

运输

ambient

储存温度

15-25°C

SMILES字符串

[Na+].[H][C@]12CC[C@@]3([H])[C@]4([H])CC[C@H]([C@H](C)CCC([O-])=O)[C@@]4(C)[C@@H](O)C[C@]3([H])[C@@]1(C)CC[C@@H](O)C2

InChI

1S/C24H40O4.Na/c1-14(4-9-22(27)28)18-7-8-19-17-6-5-15-12-16(25)10-11-23(15,2)20(17)13-21(26)24(18,19)3;/h14-21,25-26H,4-13H2,1-3H3,(H,27,28);/q;+1/p-1/t14-,15-,16-,17+,18-,19+,20+,21+,23+,24-;/m1./s1

InChI key

FHHPUSMSKHSNKW-SMOYURAASA-M

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一般描述

Absorbance (10%, H2O, 290 nm):≤0.25.
Highly purified and intended for use as a detergent to solubilize membrane-bound proteins in their native state (absorbance: <0.25 at 290 nm, 10% H2O; aggregation number: 3-12; CMC: 2-6 mM; micellar weight: 1200-4900; pKa: 6.2). Reported to induce tyrosine phosphorylation of β-catenin and its subsequent translocation to the nucleus, promoting activation of β-catenin signaling (effective concentration 5-50 µM).
Highly purified and intended for use as a detergent to solubilize membrane-bound proteins in their native state. Reported to induce tyrosine phosphorylation of β-catenin and its subsequent translocation to the nucleus, promoting activation of β-catenin signaling (effective concentration 5-50 µM). Aggregation number: 3-12.

应用


  • Treatment of mucocutaneous leishmaniasis - A systematic review.: Sodium deoxycholate is discussed in this systematic review as a component in treatment regimens for mucocutaneous leishmaniasis, offering comprehensive insights into current therapeutic approaches and outcomes (Fischer et al., 2024).

警告

Toxicity: Harmful (C)

制备说明

Do not use with Mn2+ in solution.

重悬

Following reconstitution, refrigerate (4°C). Stock solutions are stable for up to 6 months at 4°C. Discard if bacterial or fungal growth is observed.

其他说明

Pai, R., et al. Mol. Biol. Cell15, 2156.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
ULTROL is a registered trademark of Merck KGaA, Darmstadt, Germany

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Acute Tox. 4 Oral

储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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