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Merck
CN

220202

CHAPSO

Unique detergent with high CMC that solubilizes membrane-bound proteins in their native state.

别名:

CHAPSO, 3-[(3-Cholamidopropyl)dimethylammonio]-2-hydroxy-1-propanesulfonate

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关于此项目

经验公式（希尔记法）:
C32H58N2O8S
化学文摘社编号:
82473-24-3
分子量:
630.88
UNSPSC Code:
12161902
NACRES:
NA.25
MDL number:
MFCD00081079

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产品名称

CHAPSO, Unique detergent with high CMC that solubilizes membrane-bound proteins in their native state.

SMILES string

[S](=O)(=O)([O-])CC(O)C[N+](CCCNC(=O)CC[C@H]([C@@H]1[C@@]2([C@H]([C@H]3[C@@H]([C@@]4([C@H](C[C@H]3O)C[C@@H](CC4)O)C)C[C@@H]2O)CC1)C)C)(C)C

InChI

1S/C32H58N2O8S/c1-20(7-10-29(39)33-13-6-14-34(4,5)18-23(36)19-43(40,41)42)24-8-9-25-30-26(17-28(38)32(24,25)3)31(2)12-11-22(35)15-21(31)16-27(30)37/h20-28,30,35-38H,6-19H2,1-5H3,(H-,33,39,40,41,42)/t20-,21+,22-,23?,24-,25+,26+,27-,28+,30+,31+,32-/m1/s1

InChI key

GUQQBLRVXOUDTN-XOHPMCGNSA-N

assay

>98% (TLC)

form

solid

mol wt

micellar wt 9960

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

aggregation number

11

color

white

CMC

8 mM

solubility

water: soluble

shipped in

ambient

storage temp.

2-8°C

Quality Level

100

相关类别

Disclaimer

Toxicity: Standard Handling (A)

General description

Unique detergent with high CMC that solubilizes membrane-bound proteins in their native state (aggregation number: 11; CMC: 8 mM; micellar weight: 9960). Capable of solubilizing the opiate receptor to a state exhibiting reversible binding of opiates. Has a higher solubility than CHAPS because of its more polar head group.

Other Notes

Simonds, W.F., et al. 1980. Proc. Natl. Acad. Sci. USA77, 4623.

Preparation Note

Following reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 3 days at 4°C.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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