PRAK Protein, unactive

FUNCTION: SwissProt: Q8IW41 # Mediates stress-induced small heat shock protein 27 phosphorylation.
SIZE: 473 amino acids; 54220 Da
SUBUNIT: Interacts with SQSTM1.
SUBCELLULAR LOCATION: Cytoplasm (Probable). Nucleus. Note=Also observed in the nucleus.
TISSUE SPECIFICITY: Expressed ubiquitously.
PTM: Phosphorylated on Thr-182; which is the regulatory phosphorylation site and is located on the T-loop/loop 12.
SIMILARITY: SwissProt: Q8IW41 ## Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. & Contains 1 protein kinase domain.

Also available in 50 mg size (cat#14-335)

Routinely evaluated by phosphorylation of PRAK Substrate Peptide

routinely evaluated by phosphorylation of PRAK Substrate Peptide

54kDa

Stable for 6 months at -20C

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

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