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Merck
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MAPKAPK5

mitogen-activated protein kinase-activated protein kinase 5

别名:
MAPKAP-K5, MK-5, MK5, PRAK
物种:
UniProtKB ID:
基因ID:
  • Human(8550) Summary: The protein encoded by this gene is a tumor suppressor and member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. The encoded protein is found in the nucleus but translocates to the cytoplasm upon phosphorylation and activation. This kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Nov 2012]
  • Mouse(17165) MAP kinase-activated protein kinase 5
  • Rat(498183) mitogen-activated protein kinase-activated protein kinase 5
  • naked mole-rat(101703557) mitogen-activated protein kinase-activated protein kinase 5
  • cow(535625) mitogen-activated protein kinase-activated protein kinase 5
  • Zebrafish(436608) mitogen-activated protein kinase-activated protein kinase 5
  • dog(477480) mitogen-activated protein kinase-activated protein kinase 5
  • domestic guinea pig(100730794) mitogen-activated protein kinase-activated protein kinase 5
  • sheep(101116258) mitogen-activated protein kinase-activated protein kinase 5
  • domestic cat(101082699) mitogen-activated protein kinase-activated protein kinase 5
  • chicken(373929) mitogen-activated protein kinase-activated protein kinase 5
  • Horse(100057579) mitogen-activated protein kinase-activated protein kinase 5

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Antibodies

货号
说明
物种反应性
应用
Anti-MAPKAPK5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
Anti-MAPKAPK5 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
western blot
Monoclonal Anti-MAPKAPK5 antibody produced in mouse, clone 2D5, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
western blot
Monoclonal Anti-MAPKAPK5, (C-terminal) antibody produced in mouse, clone 3D7, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
immunofluorescence

western blot
Anti-MAPKAPK5 antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse
应用
ELISA
immunohistochemistry

Proteins

货号
说明
物种
PRAK Protein, unactive, ,
物种
human

esiRNA

货号
说明
物种
MISSION® 长非编码 esiRNA, targeting human MAPKAPK5,
物种
human
MISSION® esiRNA, targeting human MAPKAPK5 (2),
物种
human