产品名称
Eshmuno® A, Eshmuno® A, affinity
ligand
protein A
form
resin
specific analyte(s)
MAbs
manufacturer/tradename
Eshmuno®
parameter
>500 cm/hr flow rate
8 bar max. pressure
matrix active group
polymer, polyvinyl ether
mean particle size
50 μm
capacity
40-55 mg/mL binding capacity
transition temp
flash point 35 °C (calculated)
separation technique
affinity
storage temp.
2-8°C
Quality Level
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Analysis Note
显微分析：球形颗粒，无团聚，无细粒
粒径(30 – 70 µm)： ≥ 80 %
内毒素： ≤ 1.00 EU/ml
TAMC（好氧微生物总数）： ≤ 100 CFU/ml
TYMC（酵母和霉菌总数）： ≤ 100 CFU/ml
容量(IgG)： ≥ 55 mg/ml
泄漏（蛋白质A）： ≤ 100 ppm
Features and Benefits
- 强化工艺，产生高结合能力、卓越的流动性和出色的HCP降低性能。
- 产品纯度更高，病毒清除更一致，聚集体去除率更高，fab发现率更低，蛋白A浸出率更低
- 高流速下的高动态结合能力
- 聚集体去除、碱性稳定性和酸洗兼容性
General description
Packaging
- 1.20089.0100: Eshmuno® A树脂100 ml
- 1.20089.9010: Eshmuno® A树脂10 L
- 1.20089.0010: Eshmuno® A树脂10 ml
- 1.20089.0500: Eshmuno® A树脂500 ml
- 1.20089.5000: Eshmuno® A树脂5 L
Legal Information
signalword
Warning
hcodes
Hazard Classifications
Flam. Liq. 3
存储类别
3 - Flammable liquids
wgk
WGK 1
flash_point_f
95.0 °F
flash_point_c
35 °C
商品
Move towards Biopharma 4.0 and realize the benefits of multi column capture chromatography for intensified downstream process development.
Multi column chromatography has the benefit of using less resin, increasing productivity, and enabling continuous processing. Learn more in this technical article.
相关内容
This page summarizes key considerations related to regulatory expectations for biomanufacturing including chemicals and polymeric materials. For chemicals, topics include nitrosamines and elemental impurities, and for polymeric materials such as filters and single-use assemblies, the focus is qualification and extractable and leachable testing.
Learn more on mAb downstream processing, more specifically affinity chromatography and the relevant associated products.
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