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Merck
CN

1.16881

Millipore

Fractogel EMD TMAE (M)

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别名:
Fractogel® EMD TMAE (M)
UNSPSC代码:
41115711

ligand

(Trimethylammoniumethyl)

质量水平

描述

strong anion exchanger, suspension in 20% ethanol and 150 mM NaCl (40-90 µm)

无菌性

sterile (Caustic Stable)

产品线

Fractogel®

形式

resin

参数

240 cm/hr flow rate
8 bar max. pressure

基质活性基团

methacrylate

平均粒径

40-90 μm

容量

100 mg binding capacity (BSA/mg of resin)

转变温度

flash point 35 °C (calculated)

密度

1.430 g/cm3 at 20 °C

堆积密度

1000 kg/m3

应用

gene therapy
mAb
recombinant protein

分离技术

anion exchange
strong anion exchange

储存温度

no temp limit

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一般描述

Strong anion exchange Fractogel® resin featuring the tentacle technology with a trimethylammoniumethyl functional group, for purification of acidic and neutral proteins and peptides from multiple sources, DNA and virus removal, plasmid isolation, vaccine purification, and more

特点和优势

Fractogel® EMD TMAE (M) enables:

  • High protein loading conditions resulting in good selectivity and resolution with the tentacle technology
  • Excellent binding to large viruses at increased loading
  • Homogenous binding with high selectivity and purity
  • Reduce operating costs and resin replacement with enduring durability - allowing for multiple cycles of column regeneration and sanitization
  • Compatibility with 2.5 % (v/v) aqueous benzyl alcohol containing 150 mM NaCl storage solution

包装

  • 1.16881.0100: Fractogel® EMD TMAE (M) Resin 100ml
  • 1.16881.0010: Fractogel® EMD TMAE (M) Resin 10ml
  • 1.16881.0500: Fractogel® EMD TMAE (M) Resin 500ml
  • 1.16881.0050: Fractogel® EMD TMAE (M) Resin 50ml
Plastic bottle

分析说明

Appearance: Milky turbid suspension, free from impurities (foreign particles)
Microscopic evaluation: Uniform spherical particles,no agglomerates,no fines
Extractable matter (water): ≤ 0.03 %
Cerium: ≤ 1 µg/g
Pressure drop(column: ID=1.6 cm, L=10 cm at 5 ml/min): ≤ 1.0 bar
Particle size (d10): 37 - 45 µm
Particle size (d50): 48 - 60 µm
Particle size (d90): 63 - 77 µm
Colony forming units (TAMC + TYMC): ≤ 100 CFU/ml
Endotoxins: ≤ 1.00 EU/ml
Protein binding capacity (bovine serum albumin): 80 - 120 mg/ml
Functional test (b:a): ≤ 0.25
Functional test: Separation of conalbumin and human serum albumin

法律信息

FRACTOGEL is a registered trademark of Merck KGaA, Darmstadt, Germany

象形图

Flame

警示用语:

Warning

危险声明

危险分类

Flam. Liq. 3

WGK

WGK 1

闪点(°F)

95.0 °F

闪点(°C)

35 °C


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