推荐产品
Agency
BP
ChP
JPC
Ph. Eur.
USP
质量水平
蒸汽压
0.0267 hPa ( 20 °C)
描述
EMPROVE® EXPERT Ph Eur,BP,JPC,USP,ACS
产品线
EMPROVE® EXPERT
表单
solid
特点
RNase and DNase free
pH值(酸碱度)
10.2-10.6 (20 °C, 6 g/L in H2O)
有效pH范围
7-9
pKa (25 °C)
8.1
沸点
219-220 °C/10 mmHg (lit.)
219-220 °C/13.3 hPa
mp
167-172 °C (lit.)
密度
1.35 g/cm3 at 23 °C
应用
liquid formulation
pharmaceutical
semi-solid formulation
储存温度
no temp limit
SMILES字符串
NC(CO)(CO)CO
InChI
1S/C4H11NO3/c5-4(1-6,2-7)3-8/h6-8H,1-3,5H2
InChI key
LENZDBCJOHFCAS-UHFFFAOYSA-N
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一般描述
Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.
应用
Tris(hydroxymethyl)aminomethane (Trometamol) is a commonly used buffer component in biomolecule downstream chromatography steps as well as final liquid formulation.
Due to its low polyoxymethylene limits, Tris(hydroxymethyl)aminomethane (Trometamol) Emprove® Expert is suitable for use at elevated concentrations without risking precipitation. Also, low microbial and endotoxin limits facilitate the use of this product in high-risk applications.
Due to its low polyoxymethylene limits, Tris(hydroxymethyl)aminomethane (Trometamol) Emprove® Expert is suitable for use at elevated concentrations without risking precipitation. Also, low microbial and endotoxin limits facilitate the use of this product in high-risk applications.
法律信息
Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany
应用
储存分类代码
11 - Combustible Solids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
商品
This overview describes the challenges when developing parenteral formulations and strategies to overcome them and reduce the risk of production.
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