跳转至内容
Merck
CN

1.08307

SAFC

高纯度三(羟甲基)胺基甲烷(氨基丁三醇)

(Trometamol) high purity, EMPROVE® EXPERT, Ph. Eur., BP, ChP, JPC, USP

Pharma Manufacturing

登录查看公司和协议定价

别名:
三(羟甲基)氨基甲烷, 2-氨基-2-(羟甲基)-1,3-丙二醇, THAM, Tris 碱, 氨基丁三醇
线性分子式:
NH2C(CH2OH)3
CAS号:
分子量:
121.14
Beilstein:
741883
MDL编号:
UNSPSC代码:
12352209
EC索引号:
201-064-4

Agency

BP
ChP
JPC
Ph. Eur.
USP

质量水平

蒸汽压

0.0267 hPa ( 20 °C)

描述

EMPROVE® EXPERT Ph Eur,BP,JPC,USP,ACS

产品线

EMPROVE® EXPERT

形式

solid

特点

RNase and DNase free

pH值(酸碱度)

10.2-10.6 (20 °C, 6 g/L in H2O)

有效pH范围

7-9

pKa (25 °C)

8.1

bp

219-220 °C/10 mmHg (lit.)
219-220 °C/13.3 hPa

mp

167-172 °C (lit.)

密度

1.35 g/cm3 at 23 °C

应用

liquid formulation
pharmaceutical
semi-solid formulation

储存温度

no temp limit

SMILES字符串

NC(CO)(CO)CO

InChI

1S/C4H11NO3/c5-4(1-6,2-7)3-8/h6-8H,1-3,5H2

InChI key

LENZDBCJOHFCAS-UHFFFAOYSA-N

正在寻找类似产品? 访问 产品对比指南

一般描述

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

应用

Tris(hydroxymethyl)aminomethane (Trometamol) is a commonly used buffer component in biomolecule downstream chromatography steps as well as final liquid formulation.
Due to its low polyoxymethylene limits, Tris(hydroxymethyl)aminomethane (Trometamol) Emprove® Expert is suitable for use at elevated concentrations without risking precipitation. Also, low microbial and endotoxin limits facilitate the use of this product in high-risk applications.

法律信息

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

新产品

分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ (Lot或Batch)字后找到。

已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

商品

This overview describes the challenges when developing parenteral formulations and strategies to overcome them and reduce the risk of production.

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门