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产品线
EMPROVE® EXPERT
质量水平
环保替代产品特性
Waste Prevention
Learn more about the Principles of Green Chemistry.
sustainability
Greener Alternative Product
应用
pharma/biopharma processes
环保替代产品分类
储存温度
−20°C
一般描述
The best-in-class solution for nucleic acid removal at high salt concentration in Bioprocessing
We are committed to bringing you Greener AlternativeProducts, which belongs to one of the four categories of greener alternatives .This product is a Design for Sustainability (DfS) developed product. Click hereto view its DfS scorecard.
应用
The Benzonase® Salt Tolerant endonuclease Emprove® Expert is a new enzyme, different in amino acids sequence from other Benzonase® endonuclease references. It was designed with state-of-the-art protein engineering capabilities, to ensure the highest activity at high salt concentrations. The protein is a monomer with a molecular weight of about 27 kDa . The protein has an isoelectric point (pI) at pH 9.68. It is functional between pH 6 and 10, and from 0 °C to above 37 °C. Mg2+ (1–2 mM) is required for enzyme activity.
包装
- 80,000 Units
- 400,000 Units
- 4,000,000 Units + 40, 000 Units tailgate sample
法律信息
Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
储存分类代码
10 - Combustible liquids
WGK
WGK 1
法规信息
新产品
商品
本文介绍了细胞裂解的主要考虑因素,以及如何通过高盐浓度配合耐高盐核酸内切酶提高AAV载体生产工艺的病毒滴度和感染能力。
This page describes key considerations for cell lysis and how the combination of a high salt concentration and a salt tolerant endonuclease can be used to increase vector titer and infectivity during AAV vector manufacturing.
Benzonase®endonuclease efficiently removes nucleic acid contaminants from viral production, crucial for cell and gene therapies and vaccines.
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