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Merck
CN

1.03140

SAFC

Parteck® SI 400 (山梨醇)

EMPROVE® ESSENTIAL, Ph. Eur., BP, NF, FCC, E 420, JSFA

Pharma Manufacturing

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别名:
Parteck®山梨糖醇
经验公式(希尔记法):
C6H14O6
CAS号:
分子量:
182.17
MDL编号:
UNSPSC代码:
12352201
E编号:
E420
EC索引号:
200-061-5

Agency

BP
JSFA
NF
Ph. Eur.

质量水平

管理合规性

FCC

产品线

EMPROVE® ESSENTIAL

形式

coarse powder

自燃温度

420 °C

质量

E 420

粒径

(see specification)

pH值(酸碱度)

6-7 (20 °C, 100 g/L in H2O)

mp

94-96 °C

转变温度

flash point >100 °C

溶解性

2350 g/L

密度

1.49 g/cm3 at 20 °C

应用

liquid formulation
pharmaceutical
solid formulation

储存温度

2-25°C

InChI

1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2

InChI key

FBPFZTCFMRRESA-UHFFFAOYSA-N

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一般描述

With formulation challenges in mind, we have used particle engineering technologies to develop functional excipients specifically for solid dosage forms. The products in our Parteck® portfolio feature unique particle properties tailored for excellent performance in tableting processes, for specific drug delivery technologies, or for solubility enhancement.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

应用

Parteck® SI excipient is a directly compressible sorbitol which combines excellent tableting behavior, resulting in very robust and shiny tablets, with a pleasant mouthfeel and taste. The unique and large surface area allows for a fast disintegration and dissolution, even at high tablet hardnesses and supports a good content uniformity of low dose API formulations. Parteck® SI excipient comes in a variety of particle sizes and qualities to meet the needs of a very wide range of applications.

特点和优势

  • Excellent direct compression properties
  • High dilution and adsorption capacity
  • Larger and highly structured surface area
  • Low hygroscopicity
  • Low amount of reducing sugars

法律信息

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
PARTECK is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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商品

This article describes the use of excipients to help address API stability issues.

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