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Merck
CN

1.02465

氯化钙 二水合物

EMPROVE® API, Ph. Eur., BP, ChP, JP, USP

别名:

Calcium dichloride

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经验公式（希尔记法）:
CaCl2 · 2H2O
化学文摘社编号:
10035-04-8
分子量:
147.01
UNSPSC Code:
12352302
EC Index Number:
600-075-5
MDL number:
MFCD00149613

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产品名称

氯化钙 二水合物, EMPROVE® API, Ph. Eur., BP, ChP, JP, USP

InChI

1S/Ca.2ClH.2H2O/h;2*1H;2*1H2/q+2;;;;/p-2

SMILES string

O.O.Cl[Ca]Cl

InChI key

LLSDKQJKOVVTOJ-UHFFFAOYSA-L

agency

BP
ChP
JP
Ph. Eur.
USP

product line

EMPROVE® API

form

solid

potency

2630 mg/kg LD50, skin (Rat)

pH

4.5-8.5 (20 °C, 50 g/L in H2O)

mp

176 °C (dec.) (lit.)

solubility

soluble

application(s)

liquid formulation
ophthalmics
pharmaceutical
semi-solid formulation
solid formulation

storage temp.

2-25°C

Quality Level

600

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相关类别

Application

Calcium chloride dihydrate is typically used in clinical nutrition and in infusion. Calcium Chloride dihydrate cryst. Emprove® API is manufactured according to ICH Q7 guidelines. A CEP and an US-DMF are available.

General description

We provide industry-leading production know-how and comprehensive regulatory support for high-quality APIs, backed by nearly 200 years of experience. From a complete portfolio of innovative folates to custom synthesis, our customized and scalable solutions meet your specific production needs. As part of our EMPROVE® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H319

Hazard Classifications

Eye Irrit. 2

存储类别

13 - Non Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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Strategies for the Development of Safe and Effective Pediatric Formulations

Medicine for children poses unique formulation challenges compared to adults. Consider developmental physiology and age specifics when designing pharmaceuticals. Quality issues can severely impact patient safety. Therefore, excipient quality, supplier selection, and supply chain security are crucial, particularly for pediatric formulations.

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Pediatric Formulations

Developing formulations specifically for infants and children is increasingly important. To help you master these challenges effectively, we offer an extensive portfolio of well-established high-quality excipients and APIs for pediatric pharmaceutical formulations that are proven in practice.

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