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Merck
CN
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文件

安全信息

1.02367

SAFC

氯化镁 六水合物

cryst. EMPROVE® API Ph Eur,BP,JPC,USP

Pharma Manufacturing

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别名:
Magnesium dichloride
线性分子式:
MgCl2 · 6H2O
CAS号:
7791-18-6
分子量:
203.30
MDL编号:
MFCD00149781
UNSPSC代码:
12352302
EC索引号:
232-094-6

Agency

BP
JPC
Ph. Eur.
USP

质量水平

600

产品线

EMPROVE® API

形式

solid

效能

8100 mg/kg LD50, oral (Rat)

pH值（酸碱度）

4.5-7.0 (20 °C, 50 g/L in H2O)

mp

117 °C (decomposition)

溶解性

468.7 g/L

应用

liquid formulation
ophthalmics
parenterals
pharmaceutical
semi-solid formulation
solid formulation

储存温度

2-25°C

SMILES字符串

O.O.O.O.O.O.Cl[Mg]Cl

InChI

1S/2ClH.Mg.6H2O/h2*1H;;6*1H2/q;;+2;;;;;;/p-2

InChI key

DHRRIBDTHFBPNG-UHFFFAOYSA-L

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相关类别

一般描述

We provide industry-leading production know-how and comprehensive regulatory support for high-quality APIs, backed by nearly 200 years of experience. From a complete portfolio of innovative folates to custom synthesis, our customized and scalable solutions meet your specific production needs. As part of our EMPROVE® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

应用

Magnesium chloride hexahydrate is used in clinical nutrition and in infusion. Magnesium Chloride hexahydrate cryst. Emprove® API is manufactured according to ICH Q7 guidelines. A CEP and an US-DMF are available.

法律信息

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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Strategies for the Development of Safe and Effective Pediatric Formulations

Medicine for children poses unique formulation challenges compared to adults. Consider developmental physiology and age specifics when designing pharmaceuticals. Quality issues can severely impact patient safety. Therefore, excipient quality, supplier selection, and supply chain security are crucial, particularly for pediatric formulations.

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Pediatric Formulations

Developing formulations specifically for infants and children is increasingly important. To help you master these challenges effectively, we offer an extensive portfolio of well-established high-quality excipients and APIs for pediatric pharmaceutical formulations that are proven in practice.

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