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Merck
CN

1.00681

SAFC

琥珀酸

crystalline, EMPROVE® ESSENTIAL, ChP, NF, JPE, ACS

Pharma Manufacturing

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别名:
丁二酸
线性分子式:
HOOCCH2CH2COOH
CAS号:
分子量:
118.09
Beilstein:
1754069
MDL编号:
UNSPSC代码:
12352106
EC索引号:
203-740-4

等级

ACS reagent

质量水平

Agency

ChP
JPE
NF

产品线

EMPROVE® ESSENTIAL

检测方案

99.0-100.5% (HPLC)

形式

crystalline
solid

自燃温度

470 °C

技术

API processing | cocrystal formation: suitable
API processing | salt formation: suitable

bp

235 °C (lit.)
235 °C/1013 hPa

mp

184-186 °C (lit.)

转变温度

flash point 206 °C

溶解性

58 g/L

密度

1.56 g/cm3 at 20 °C

痕量阴离子

chloride (Cl-): ≤0.001%
phosphate (PO43-): ≤0.001%
sulfate (SO42-): ≤0.003%

痕量阳离子

As: ≤0.0002%
Fe: ≤5 ppm
heavy metals (as Pb): ≤0.0020%
heavy metals (as Pb): ≤5 ppm

应用

liquid formulation
pharma/biopharma processes
pharmaceutical
solid formulation

储存温度

2-30°C

SMILES字符串

OC(=O)CCC(O)=O

InChI

1S/C4H6O4/c5-3(6)1-2-4(7)8/h1-2H2,(H,5,6)(H,7,8)

InChI key

KDYFGRWQOYBRFD-UHFFFAOYSA-N

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一般描述

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our EMPROVE® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

应用

Succinic acid is a commonly used ingredient in pharmaceutical applications. In such applications it has been used primarily for solid oral dosage forms.

法律信息

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

象形图

Corrosion

警示用语:

Danger

危险声明

预防措施声明

危险分类

Eye Dam. 1

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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