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Merck
CN

1.00635

水杨酸标准液

fine powder EMPROVE® ESSENTIAL Ph Eur,BP,USP

别名:

Salicylic acid, 2-Hydroxybenzoic acid

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关于此项目

经验公式(希尔记法):
C7H6O3
化学文摘社编号:
分子量:
138.12
UNSPSC Code:
12352106
EC Index Number:
200-712-3
MDL number:
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产品名称

水杨酸标准液, fine powder EMPROVE® ESSENTIAL Ph Eur,BP,USP

SMILES string

[O-]c1c(cccc1)C(=O)O.[H+]

InChI

1S/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10)

InChI key

YGSDEFSMJLZEOE-UHFFFAOYSA-N

agency

BP
Ph. Eur.
USP

vapor pressure

<1 hPa ( 100 °C)

product line

EMPROVE® ESSENTIAL

assay

98.0-102.0% dry basis (HPLC)

form

solid

autoignition temp.

500 °C

potency

1250-1580 mg/kg LD50, oral (Rat)
>2000 mg/kg LD50, skin (Rat)

technique(s)

tissue culture: suitable

pH

2.4 ( in H2O, saturated solution)

bp

211 °C/1013 hPa

mp

157-159 °C

transition temp

flash point 157 °C

solubility

water: 2 g/L at 20 °C

density

1.443 g/cm3 at 20 °C

bulk density

400‑500 kg/m3

anion traces

chloride (Cl-): ≤0.0100%
sulfate (SO42-): ≤0.0200%

application(s)

liquid formulation
pharmaceutical

storage temp.

15-25°C

Quality Level

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Application

Salicylic acid is used in dermatological medicine for skin exfoliating and acne. Salicylic acid Emprove® Essential is suitable for pharmaceutical applications.

General description

We offer a range of high quality critical raw materials, solvents and reagents plus the documentation and expertise to meet stringent regulatory requirements. In addition to our comprehensive portfolio, we also offer custom manufacturing services to meet your exact needs. As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Repr. 2

存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

314.6 °F - closed cup

flash_point_c

157 °C - closed cup


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实验方案

Accurately measure the moisture content in ethanolamine (HOCHCHNH) through Karl Fischer titration, using both volumetric or coulometric methods.

With the exception of prolin, amino acids are hardly soluble in alcohols. Therefore, only the adherent moisture can be determined by the direct volumetric method.

Summary application report for analysis of moisture in Triethylamine

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