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Merck
CN

1.00263

甲酸

98-100%, EMPROVE® ESSENTIAL

别名:

甲酸

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线性分子式:
HCOOH
化学文摘社编号:
64-18-6
分子量:
46.03
EC Index Number:
200-579-1
UNSPSC Code:
12352106
Beilstein/REAXYS Number:
1209246
MDL number:
MFCD00003297

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产品名称

甲酸, 98-100%, EMPROVE® ESSENTIAL

SMILES string

OC=O

InChI

1S/CH2O2/c2-1-3/h1H,(H,2,3)

InChI key

BDAGIHXWWSANSR-UHFFFAOYSA-N

vapor density

1.6 (vs air)

vapor pressure

44.8 mmHg ( 20 °C)

product line

EMPROVE® ESSENTIAL

assay

≥98% (alkalimetric)

form

liquid

autoignition temp.

1004 °F

expl. lim.

12-38 % (v/v)
57 %

concentration

98-100%

technique(s)

API processing | polymorph screening: suitable
API processing | salt formation: suitable

refractive index

n20/D 1.370 (lit.)

pH

2.2 (20 °C, 10 g/L in H2O)

bp

100-101 °C (lit.)
101 °C/1013 hPa

mp

8.2-8.4 °C (lit.)

transition temp

flash point 49.5 °C

density

1.22 g/mL at 25 °C (lit.)

anion traces

chloride (Cl-): ≤0.001%
sulfate (SO42-): ≤0.004%
sulfite (SO32-): ≤0.002%

cation traces

As: ≤0.0003%
Cu: ≤0.002%
Pb: ≤0.001%
Zn: ≤0.002%
heavy metals (as Pb): ≤0.0005%

application(s)

liquid formulation
pharmaceutical

storage temp.

15-25°C

Quality Level

500

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Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Application

Formic acid can be used as acidifying agent and buffer component in a variety of pharmaceutical formulations and processes.

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

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Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1A

supp_hazards

EUH071

存储类别

3 - Flammable liquids

wgk

WGK 1

flash_point_f

121.1 °F

flash_point_c

49.5 °C

法规信息

危险化学品
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