推荐产品
生物来源
mouse
质量水平
抗体形式
purified antibody
抗体产品类型
primary antibodies
克隆
2F3.2, monoclonal
种属反应性
human
制造商/商品名称
Upstate®
技术
flow cytometry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
同位素/亚型
IgG2a
NCBI登记号
UniProt登记号
运输
wet ice
靶向翻译后修饰
unmodified
基因信息
human ... ZAP70(7535)
相关类别
一般描述
Note: This product is for research use only. It is not manufacured for diagnostic or therapeutic use in humans or animals.
特异性
human ZAP-70, does not recognize murine ZAP-70
免疫原
GST-fusion to tandem SH2 domains of human ZAP-70 corresponding to residues 1-254
应用
Detect ZAP-70 using this Anti-ZAP-70 Antibody, clone 2F3.2 validated for use in FC, IH, IP & WB.
Research Category
Signaling
Signaling
Research Sub Category
Immunological Signaling
Immunological Signaling
质量
routinely evaluated on RIPA lysates prepared from Jurkat cells or Hut-78 cell lysate
目标描述
70kDa
外形
Protein G Chromatography
Format: Purified
PBS
储存及稳定性
2 years at -20°C
分析说明
Control
Positive Antigen Control: Catalog #12-303, Jurkat cell lysate.
Positive Antigen Control: Catalog #12-303, Jurkat cell lysate.
法律信息
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
12 - Non Combustible Liquids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Marta Crespo et al.
The New England journal of medicine, 348(18), 1764-1775 (2003-05-02)
The mutational status of immunoglobulin heavy-chain variable-region (IgVH) genes in the leukemic cells of chronic lymphocytic leukemia (CLL) is an important prognostic factor in the disease. We investigated whether the expression of ZAP-70 by CLL cells correlated with the IgVH
TCR signaling: another Abl-bodied kinase joins the cascade.
Wange, Ronald L
Current Biology, 14, R562-R564 (2004)
D H Chu et al.
Immunological reviews, 165, 167-180 (1998-12-16)
The processes of T-cell development and activation employ similar immature and mature receptors as well as similar signal transduction pathways to achieve different outcomes. Many signaling molecules are shared between the receptor signaling pathways, including two families of cytoplasmic protein
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