04-953
抗磷酸化-Smad2（Ser465/467）抗体，克隆A5S，兔单克隆
culture supernatant, clone A5S, Upstate®
别名:
Anti-Anti-CHTD8, Anti-Anti-JV18, Anti-Anti-JV18-1, Anti-Anti-LDS6, Anti-Anti-MADH2, Anti-Anti-MADR2, Anti-Anti-hMAD-2, Anti-Anti-hSMAD2
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100 μG
¥3,815.98
About This Item
UNSPSC代码:
12352203
eCl@ss:
32160702
NACRES:
NA.41
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生物来源
rabbit
质量水平
抗体形式
culture supernatant
抗体产品类型
primary antibodies
克隆
A5S, monoclonal
种属反应性
human, zebrafish, mouse, canine
制造商/商品名称
Upstate®
技术
western blot: suitable
同位素/亚型
IgG
NCBI登记号
1 of 4
此商品 | NA70 | CC12 | OP03 |
|---|---|---|---|
| species reactivity human | species reactivity human | species reactivity human, mouse, rat | species reactivity rabbit, monkey, human, mouse, rat |
| antibody form purified antibody | antibody form purified antibody | antibody form purified antibody | antibody form purified antibody |
| biological source mouse | biological source mouse | biological source mouse | biological source mouse |
| shipped in wet ice | shipped in wet ice | shipped in wet ice | shipped in wet ice |
| isotype IgG1 | isotype IgG1 | isotype IgG2a | isotype IgG2a |
一般描述
SMAD2或MAD-mothers against decapentaplegic-homolog是一种多肽，顾名思义，是果蝇基因：“Mothers against decepentaplegic”的同系物它属于SMAD蛋白家族，该家族又属于TGFb调节子超家族。像其他许多TGFb家族成员一样，SMAD2液参与细胞信号转导的调节。SMAD2可调节激活素和TGFb′s的信号。它可与SMAD锚相互作用激活受体（SARA）。配体的结合会引起SMAD2蛋白的磷酸化，从而与SARA的解离并与SMAD4缔合。随后，它被转移至细胞核，与其他蛋白质形成复合物并充当转录因子。SMAD2是受受体调节的SMAD（R-SMAD），并由骨形态发生蛋白1型受体激酶激活。
特异性
根据序列同源性预测与非洲爪蟾发生交叉反应。
识别磷酸化Smad2。与Smad3没有交叉反应。
免疫原
对应于人Smad2 Ser465/467位点周围氨基酸[pS]M[pS]的KLH偶联合成肽
应用
使用抗磷酸化Smad2（Ser465/467）抗体，克隆A5S（兔单克隆抗体）检测磷酸化Smad2（Ser465/467），该抗体已证明可在WB中发挥作用。
质量
已通过免疫印迹分析进行常规评估。
目标描述
55-60 kDa
联系
替代：05-953
分析说明
对照
HL60细胞裂解液，经TGFa处理的HepG2细胞或经TGF处理的HepG2细胞β
HL60细胞裂解液，经TGFa处理的HepG2细胞或经TGF处理的HepG2细胞β
其他说明
浓度：请参考批次特异性浓缩物的分析证书。
法律信息
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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储存分类代码
10 - Combustible liquids
WGK
WGK 2
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