产品名称
抗-Akt1/PKBα抗体(克隆W24 | 04-796), clone AW24, from rabbit
biological source
rabbit
conjugate
unconjugated
antibody form
culture supernatant
antibody product type
primary antibodies
clone
AW24, monoclonal
species reactivity
human, rat, mouse
technique(s)
immunoprecipitation (IP): suitable
western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... AKT1(207)
Application
研究类别
信号传导
信号传导
抗-Akt11抗体(克隆AW24)可检测Akt1/PKB水平α&已有相关文献发表& 经验证可用于 WB & IP。
研究子类别
PI3K、Akt & mTOR 信号传导
PI3K、Akt & mTOR 信号传导
Biochem/physiol Actions
该抗体可识别Akt1/PKBα。
Analysis Note
对照
HEK293 细胞裂解液
HEK293 细胞裂解液
已通过蛋白质印迹对人HEK293细胞的RIPA裂解液进行了评估。
蛋白质印迹分析:该抗体的1:1,000稀释液在人HEK293细胞的RIPA裂解液中检测到Akt1/PKBα。
蛋白质印迹分析:该抗体的1:1,000稀释液在人HEK293细胞的RIPA裂解液中检测到Akt1/PKBα。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
AKT1基因编码的丝氨酸/苏氨酸蛋白激酶在血清饥饿的原代和永生化成纤维细胞中催化失活。AKT1 和相关的AKT2 由血小板衍生生长因子激活。激活是迅速的、特异性的。在发育中的神经系统中,AKT是诱导经元存活的生长因子的关键介导因子。存活因子通过激活丝氨酸/苏氨酸激酶AKT1,能够以与转录无关的形式抑制细胞凋亡。然后,AKT1可以使凋亡机制的组分磷酸化并失活。已经发现了该基因的多个 可变剪接的转录变体。
~60 kDa
Immunogen
对应于大鼠Akt1/PKBαC 末端(残基 466-480)的合成肽(C-RPHFPQFSYSASGTA)。
表位:C端
Other Notes
替代:05-796
Physical form
含0.05% 叠氮化钠中的培养上清液
含0.05% 叠氮化钠的培养上清液
形式:纯化
Preparation Note
自收到之日起在-20ºC可稳定保存1年。
处理建议:收到后,在取下瓶盖之前,将小瓶离心并轻轻混合溶液。分装到微量离心管中,并储存于-20°C。避免反复冻融循环,以免损坏IgG和影响产品性能。
处理建议:收到后,在取下瓶盖之前,将小瓶离心并轻轻混合溶液。分装到微量离心管中,并储存于-20°C。避免反复冻融循环,以免损坏IgG和影响产品性能。
未找到合适的产品?
试试我们的产品选型工具.
存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
María de la Fuente-Fernández et al.
Antioxidants (Basel, Switzerland), 9(4) (2020-04-25)
The incidence of metabolic syndrome (MetS) is increasing worldwide which makes necessary the finding of new strategies to treat and/or prevent it. The aim of this study was to analyze the possible beneficial effects of a carob fruit extract (CSAT+®)
Supplementation with a New Standardized Extract of Green and Black Tea Exerts Antiadipogenic Effects and Prevents Insulin Resistance in Mice with Metabolic Syndrome.
De la Fuente-Mu??oz, et al.
International Journal of Molecular Sciences, 24 (2023)
Daniel González-Hedström et al.
Antioxidants (Basel, Switzerland), 9(6) (2020-06-07)
Aging is one of the major risk factors for suffering cardiovascular and metabolic diseases. Due to the increase in life expectancy, there is a strong interest in the search for anti-aging strategies to treat and prevent these aging-induced disorders. Both
María C Burguete et al.
Journal of neuroendocrinology, 31(8), e12751-e12751 (2019-05-28)
Because neuroprotection in stroke should be revisited in the era of recanalisation, the present study analysed the potential neuroprotective effect of the selective oestrogen receptor modulator, bazedoxifene acetate (BZA), in an animal model of diabetic ischaemic stroke that mimics thrombectomy
Ming-Chun Hung et al.
Cell & bioscience, 12(1), 122-122 (2022-08-03)
Constitutive activation of PI3K signaling has been well recognized in a subset of small cell lung cancer (SCLC), the cancer type which has the most aggressive clinical course amongst pulmonary tumors. Whereas cancers that acquire a mutation/copy gain in PIK3CA
我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持