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Merck
CN

04-796

抗-Akt1/PKBα抗体(克隆W24 | 04-796)

clone AW24, from rabbit

别名:

AKT1 kinase, Protein kinase B, RAC-alpha serine/threonine-protein kinase, rac protein kinase alpha, v-akt murine thymoma viral oncogene homolog 1

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
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产品名称

抗-Akt1/PKBα抗体(克隆W24 | 04-796), clone AW24, from rabbit

biological source

rabbit

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

AW24, monoclonal

species reactivity

human, rat, mouse

technique(s)

immunoprecipitation (IP): suitable
western blot: suitable

isotype

IgG

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Quality Level

Gene Information

human ... AKT1(207)

Application

研究类别
信号传导
抗-Akt11抗体(克隆AW24)可检测Akt1/PKB水平α&已有相关文献发表& 经验证可用于 WB & IP。
研究子类别
PI3K、Akt & mTOR 信号传导

Biochem/physiol Actions

该抗体可识别Akt1/PKBα。

Analysis Note

对照
HEK293 细胞裂解液
已通过蛋白质印迹对人HEK293细胞的RIPA裂解液进行了评估。
蛋白质印迹分析:该抗体的1:1,000稀释液在人HEK293细胞的RIPA裂解液中检测到Akt1/PKBα。

Disclaimer

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

General description

AKT1基因编码的丝氨酸/苏氨酸蛋白激酶在血清饥饿的原代和永生化成纤维细胞中催化失活。AKT1 和相关的AKT2 由血小板衍生生长因子激活。激活是迅速的、特异性的。在发育中的神经系统中,AKT是诱导经元存活的生长因子的关键介导因子。存活因子通过激活丝氨酸/苏氨酸激酶AKT1,能够以与转录无关的形式抑制细胞凋亡。然后,AKT1可以使凋亡机制的组分磷酸化并失活。已经发现了该基因的多个 可变剪接的转录变体。
~60 kDa

Immunogen

对应于大鼠Akt1/PKBαC 末端(残基 466-480)的合成肽(C-RPHFPQFSYSASGTA)。
表位:C端

Other Notes

替代:05-796

Physical form

含0.05% 叠氮化钠中的培养上清液
含0.05% 叠氮化钠的培养上清液
形式:纯化

Preparation Note

自收到之日起在-20ºC可稳定保存1年。
处理建议:收到后,在取下瓶盖之前,将小瓶离心并轻轻混合溶液。分装到微量离心管中,并储存于-20°C。避免反复冻融循环,以免损坏IgG和影响产品性能。

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存储类别

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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