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用途
kit sufficient for 96 wells
种属反应性
human
制造商/商品名称
SMC®
assay range
sensitivity: 0.10 pg/mL
(lower limit of quantification)
inter-assay cv: <20%
intra-assay cv: <15%
standard curve range: 0.05-50 pg/mL
技术
ELISA: suitable
single molecule counting: suitable
输入
serum
plasma
相容性
for use with SMCxPRO® and Erenna<TMSYMBOL></TMSYMBOL> (validated)
运输
wet ice
储存温度
2-8°C
一般描述
The SMC® human IL-22 High Sensitivity Immunoassay Kit contains all reagents required to perform the assay. This assay takes advantage of a standard immunoassay workflow configured in a standard plate format.
Assay protocols are similar to existing sandwich ELISA methods with two key differences:
1) Elution buffer disrupts the sandwich, separating the labeled detection antibody for quantification.
2)The Erenna and SMCxPRO® immunoassay systems detect analytes using Single Molecule Counting (SMC®) technology.
Assay protocols are similar to existing sandwich ELISA methods with two key differences:
1) Elution buffer disrupts the sandwich, separating the labeled detection antibody for quantification.
2)The Erenna and SMCxPRO® immunoassay systems detect analytes using Single Molecule Counting (SMC®) technology.
特异性
Non-human primate plasma: 4 out of 4 individuals found to be detectable.
Feline plasma: 4 out of 4 individuals found to be detectable.
Canine plasma: 4 out of 4 individuals found to be detectable.
Mouse plasma: 5 out 6 individuals found to be detectable.
Although IL-22 was detectable, the assay has not been validated for these species.
Feline plasma: 4 out of 4 individuals found to be detectable.
Canine plasma: 4 out of 4 individuals found to be detectable.
Mouse plasma: 5 out 6 individuals found to be detectable.
Although IL-22 was detectable, the assay has not been validated for these species.
法律信息
SMC is a registered trademark of Singulex
SMCxPRO is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
警示用语：
Danger
危险分类
Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Irrit. 2 - Repr. 1B
WGK
WGK 3
法规信息
新产品
Mahesh Raundhal et al.
Nature immunology, 22(4), 520-529 (2021-03-24)
Patients with myelodysplastic syndromes (MDSs) display severe anemia but the mechanisms underlying this phenotype are incompletely understood. Right open-reading-frame kinase 2 (RIOK2) encodes a protein kinase located at 5q15, a region frequently lost in patients with MDS del(5q). Here we
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