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Merck
CN

03-0160-00

SMC® 人IL-1β高灵敏度试剂盒

Used for ultrasensitive quantification of Human IL-1β in human serum and plasma

别名:

IL-1 beta Single Molecule Counting Kit, IL-1 beta immunoassay kit, IL-1 beta ultra-sensitive immunoassay, Interleukin-1 beta immunoassay kit

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NACRES:
NA.84
UNSPSC Code:
12161503
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产品名称

SMC® 人IL-1β高灵敏度试剂盒, Used for ultrasensitive quantification of Human IL-1β in human serum and plasma

manufacturer/tradename

SMC®

product line

SMC®

usage

 kit sufficient for 96 wells

species reactivity

human

technique(s)

single molecule counting: suitable

input

plasma (K2 EDTA)
serum

UniProt accession no.

compatibility

for use with FemtoQuest and SMCxPRO® instruments

shipped in

wet ice

storage temp.

2-8°C

Legal Information

SMC is a registered trademark of Singulex
SMCxPRO is a registered trademark of Merck KGaA, Darmstadt, Germany
FEMTOQUEST is a trademark of Merck KGaA, Darmstadt, Germany

Biochem/physiol Actions

发现非人类灵长类动物,大鼠,犬,猫和马样品的检出率为100%。 尽管可以检测到IL-1β,但尚未对这些物种的测定进行验证。

Disclaimer

我们的产品仅用于研究目的,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用对人类或动物。

General description

SMC® 人IL-1β高灵敏度免疫分析试剂盒包含进行分析所需的所有试剂。该测定采用以标准孔板形式配置的标准免疫测定工作流程。

测定方案与现有的夹心ELISA方法相似,但有两个主要区别:
1)洗脱缓冲液破坏夹心结构,分离标记的检测抗体以进行定量。
2)Erenna和SMCxPRO®免疫测定系统使用单分子计数(SMC®)技术检测分析物。

Analysis Note

  • Sensitivity: LLOQ 200 fg/mL* (SMCxPRO® Instrument
  • Standard Curve Range: 50-50,000 fg/mL
  • Intra-assay CV: <15%
  • Inter-assay CV: <20%
  • Linearity: Serum: 107% Plasma: 111%
  • Recovery: Serum: 85% Plasma: 83%

*Indicative LLOQ created from average of 14 independent in house runs, where >80% met same value defined with CV & Recovery +/- 20%. Refer to CoA for lot specific performance.
Inflammation & Immunology Inflammatory Disease Immune Response Autoimmune Disease

Application

Inflammatory Disease / Immune Response / Autoimmune Disease

Features and Benefits

  • High-Performance Sensitivity: The SMC®technology excels in the quantification of IL-1β in human serum and plasma, enabling highly accurate measurements.
  • Built for Confidence: With low variability and high reproducibility, you can trust your data across experiments. Whether you′re profiling inflammation or validating biomarkers, this assay delivers consistent, high-quality results.
  • Deeper Insights into Inflammation: IL-1β is a key player in autoimmune diseases, neuroinflammation, and sepsis. This assay helps you explore its role with unmatched clarity.
  • Early Biomarker Detection: The ultra-sensitive performance supports early-stage discovery and therapeutic development.

Packaging

96 well assay

pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Irrit. 2 - Repr. 1B

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

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