等级
certified reference material
质量水平
形式
liquid
特点
Snap-N-Spike®/Snap-N-Shoot®
包装
ampule of 1 mL
制造商/商品名称
Cerilliant®
浓度
1.0 mg/mL in methanol
技术
gas chromatography (GC): suitable
liquid chromatography (LC): suitable
应用
clinical testing
格式
single component solution
运输
wet ice
储存温度
−20°C
SMILES字符串
CC(CC([H])(CN)CC(O)=O)C
InChI
1S/C8H17NO2/c1-6(2)3-7(5-9)4-8(10)11/h6-7H,3-5,9H2,1-2H3,(H,10,11)
InChI key
AYXYPKUFHZROOJ-UHFFFAOYSA-N
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一般描述
Sold under the trade name Lyrica®, pregabalin is an antiepileptic drug used for treatment of seizures, fibromyalgia, diabetic peripheral neuropathy, generalized anxiety disorder, and chronic neuropathic pain. This certified reference standard is suitable for pregabalin GC/MS or LC/MS applications from forensic analysis, clinical toxicology and pain prescription monitoring to urine drug testing.
应用
- Evaluation of Pregabalin and Dexamethasone Coadministration: This study assesses the effects of Pregabalin combined with dexamethasone on preemptive multimodal analgesia and anxiety management during third molar surgeries. The trial highlighted its potential to significantly improve patient outcomes in dental procedures (Diniz et al., 2024).
- Interactions with Antiepileptic Drugs: This article explores how Pregabalin interacts with other antiepileptic drugs when used for primary and secondary stroke prevention, particularly focusing on its compatibility and potential interactions in clinical settings (Stöllberger & Finsterer, 2024).
- Molecular Docking Analysis: This research utilizes molecular docking techniques to analyze Pregabalin and other marine compounds targeting voltage-gated calcium channels, aiming to identify potential anti-epileptic molecules (Sheokand et al., 2024).
- Management of Neuropathic Pain in Cats: Focused on veterinary medicine, this review discusses the mechanisms of neuropathic pain in cats and how Pregabalin, among other treatments, can be used for multimodal pain management (Rusbridge, 2024).
- Pharmacotherapy and Noninvasive Neurostimulation: This article reviews current pharmacotherapies including Pregabalin and noninvasive neurostimulation techniques for treating neuropathic pain, providing an overview of effective pain management strategies (Spagna & Attal, 2024).
法律信息
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Lyrica is a registered trademark of C.P. Pharmaceuticals International C.V.
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
相关产品
产品编号
说明
价格
警示用语：
Danger
危险分类
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
靶器官
Eyes,Central nervous system
WGK
WGK 2
闪点(°F)
49.5 °F
闪点(°C)
9.7 °C
法规信息
危险化学品
Julia Rossmann et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1000, 84-94 (2015-07-27)
Matrix effects that occur during quantitative measurement by liquid chromatography mass spectrometry specifically when using electrospray ionization are a widely recognized phenomenon. Sample matrix compounds affect the ionization process of the target analytes, lead to a low signal response, and
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