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Merck
CN

C-045

Supelco

大麻二酚标准液 溶液

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

别名:

CBD

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About This Item

经验公式(希尔记法):
C21H30O2
CAS号:
分子量:
314.46
EC 号:
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24

等级

certified reference material

质量水平

表单

liquid

特点

SNAP-N-SPIKE®, SNAP-N-SHOOT®

包装

ampule of 1 mL

制造商/商品名称

Cerilliant®

浓度

1.0 mg/mL in methanol

技术

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

应用

cannabis testing
cannabis testing

包装形式

single component solution

储存温度

−20°C

SMILES字符串

CCCCCc1cc(O)c([C@@H]2C=C(C)CC[C@H]2C(C)=C)c(O)c1

InChI

1S/C21H30O2/c1-5-6-7-8-16-12-19(22)21(20(23)13-16)18-11-15(4)9-10-17(18)14(2)3/h11-13,17-18,22-23H,2,5-10H2,1,3-4H3/t17-,18+/m0/s1

InChI key

QHMBSVQNZZTUGM-ZWKOTPCHSA-N

基因信息

human ... CNR1(1268)

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一般描述

该认证加标溶液® 适用于通过 HPLC、GC/MS 或 LC-MS/MS 法进行大麻二酚测定,从而用于法医分析、临床毒理学、尿液药物测试和大麻效力或杂质分析测试等应用。

大麻二酚(CBD)是大麻科植物中发现的重要大麻素之一,以其非精神活性特性而闻名。它在光或热的作用下由前体大麻二酚酸脱羧形成。它具有多种治疗特性,如抗氧化、抗炎、抗菌、神经保护、抗焦虑和抗惊厥作用。

应用

该认证标准物质(CRM)还可作如下用途:
  • 使用反相高效液相色谱(RP-HPLC)结合二极管阵列检测器(DAD)测定油基质中放入 4 种大麻素
  • 开发和验证基于液相色谱-串联质谱(LC-MS/MS)的技术,用于测量大鼠高剂量大麻二酚全血样品中的大麻二酚、∆9-四氢大麻酚及其代谢物
  • 使用等密度 RP-HPLC 结合 UV 检测法同时测定不同大麻油产品中的大麻二酚和四氢大麻酚
  • 通过液-液萃取(LLE)后跟气相色谱-质谱法对头发样品中的 Δ9-四氢大麻酚、大麻酚和大麻二酚进行多重分析
  • 超声辅助提取三种不同商业外用产品中的大麻二酚,并以 GC-MS 法测定

特点和优势

  • 完全符合 ISO/IEC 17025 和 ISO 17034 认证
  • 附综合分析证书(CoA),包括稳定性、均匀性、浓度准确性、不确定性和可追溯性数据
  • 通过实时稳定性研究严格测试,以确保准确性和保质期
  • 使用合格的精密天平进行重量准备,以确保最小不确定性
  • 氩气环境下火焰密封,装入安瓿以便长期保存
  • 提供方便的 DEA 豁免格式,以提高实验室效率

法律信息

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

相关产品

产品编号
说明
价格

警示用语:

Danger

危险分类

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

靶器官

Eyes,Central nervous system

储存分类代码

3 - Flammable liquids

WGK

WGK 2

闪点(°F)

49.5 °F - closed cup

闪点(°C)

9.7 °C - closed cup

法规信息

监管及禁止进口产品

从最新的版本中选择一种:

分析证书(COA)

Lot/Batch Number

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R B Laprairie et al.
British journal of pharmacology, 172(20), 4790-4805 (2015-07-29)
Cannabidiol has been reported to act as an antagonist at cannabinoid CB1 receptors. We hypothesized that cannabidiol would inhibit cannabinoid agonist activity through negative allosteric modulation of CB1 receptors. Internalization of CB1 receptors, arrestin2 recruitment, and PLCβ3 and ERK1/2 phosphorylation
Raymond J M Niesink et al.
Addiction (Abingdon, England), 110(12), 1941-1950 (2015-08-04)
Between 2000 and 2005 the average percentage of Δ(9) -tetrahydrocannabinol (THC) in marijuana as sold in Dutch coffeeshops has increased substantially; the potency of domestic products (Nederwiet and Nederhasj) has particularly increased. In contrast with imported marijuana, Nederwiet hardly contained
Marcos Hortes N Chagas et al.
Journal of psychopharmacology (Oxford, England), 27(3), 312-316 (2013-01-25)
Cannabidiol (CBD) is one of the main components of Cannabis sativa and has a wide spectrum of action, including effects in the sleep-wake cycle. The objective of this paper is to assess the effects on sleep of acute systemic administration
Javier Fernández-Ruiz et al.
British journal of clinical pharmacology, 75(2), 323-333 (2012-05-26)
Cannabidiol (CBD) is a phytocannabinoid with therapeutic properties for numerous disorders exerted through molecular mechanisms that are yet to be completely identified. CBD acts in some experimental models as an anti-inflammatory, anticonvulsant, anti-oxidant, anti-emetic, anxiolytic and antipsychotic agent, and is
Amir Englund et al.
Journal of psychopharmacology (Oxford, England), 27(1), 19-27 (2012-10-09)
Community-based studies suggest that cannabis products that are high in Δ⁹-tetrahydrocannabinol (THC) but low in cannabidiol (CBD) are particularly hazardous for mental health. Laboratory-based studies are ideal for clarifying this issue because THC and CBD can be administered in pure

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实验方案

HPLC-UV analysis of active compounds in marijuana-infused edibles for potency testing; complex matrix requires precise methods.

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