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安全信息

C-045

Supelco

大麻二酚标准液 溶液

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

别名:

CBD

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About This Item

经验公式（希尔记法）:
C21H30O2
CAS号:
13956-29-1
分子量:
314.46
EC 号:
200-659-6
MDL编号:
MFCD00869597
UNSPSC代码:
41116107
PubChem化学物质编号:
329774791
NACRES:
NA.24

等级

certified reference material

质量水平

300

形式

liquid

特点

SNAP-N-SPIKE®, SNAP-N-SHOOT®

包装

ampule of 1 mL

制造商/商品名称

Cerilliant®

浓度

1.0 mg/mL in methanol

技术

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

应用

cannabis testing
cannabis testing

格式

single component solution

储存温度

−20°C

SMILES字符串

CCCCCc1cc(O)c([C@@H]2C=C(C)CC[C@H]2C(C)=C)c(O)c1

InChI

1S/C21H30O2/c1-5-6-7-8-16-12-19(22)21(20(23)13-16)18-11-15(4)9-10-17(18)14(2)3/h11-13,17-18,22-23H,2,5-10H2,1,3-4H3/t17-,18+/m0/s1

InChI key

QHMBSVQNZZTUGM-ZWKOTPCHSA-N

基因信息

human ... CNR1(1268)

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相关类别

一般描述

该认证加标溶液® 适用于通过 HPLC、GC/MS 或 LC-MS/MS 法进行大麻二酚测定，从而用于法医分析、临床毒理学、尿液药物测试和大麻效力或杂质分析测试等应用。

大麻二酚（CBD）是大麻科植物中发现的重要大麻素之一，以其非精神活性特性而闻名。它在光或热的作用下由前体大麻二酚酸脱羧形成。它具有多种治疗特性，如抗氧化、抗炎、抗菌、神经保护、抗焦虑和抗惊厥作用。

应用

该认证标准物质（CRM）还可作如下用途：
  • 使用反相高效液相色谱（RP-HPLC）结合二极管阵列检测器（DAD）测定油基质中放入 4 种大麻素
  • 开发和验证基于液相色谱-串联质谱（LC-MS/MS）的技术，用于测量大鼠高剂量大麻二酚全血样品中的大麻二酚、∆9-四氢大麻酚及其代谢物
  • 使用等密度 RP-HPLC 结合 UV 检测法同时测定不同大麻油产品中的大麻二酚和四氢大麻酚
  • 通过液-液萃取（LLE）后跟气相色谱-质谱法对头发样品中的 Δ9-四氢大麻酚、大麻酚和大麻二酚进行多重分析
  • 超声辅助提取三种不同商业外用产品中的大麻二酚，并以 GC-MS 法测定

特点和优势

  • 完全符合 ISO/IEC 17025 和 ISO 17034 认证
  • 附综合分析证书（CoA），包括稳定性、均匀性、浓度准确性、不确定性和可追溯性数据
  • 通过实时稳定性研究严格测试，以确保准确性和保质期
  • 使用合格的精密天平进行重量准备，以确保最小不确定性
  • 氩气环境下火焰密封，装入安瓿以便长期保存
  • 提供方便的 DEA 豁免格式，以提高实验室效率

法律信息

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

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产品编号
说明
价格

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大麻酚标准液 溶液, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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C-115

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T-003

−-Δ9-四氢大麻酚-D3标准液 溶液, 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

T-005

(−)-Δ9-四氢大麻酚标准液 溶液, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

T-011

−-Δ9-四氢大麻酚-D3标准液 溶液, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

T-032

(−)-Δ8-四氢大麻酚标准液 溶液, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

T-033

exo-THC solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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(±)-Δ9-四氢大麻酚标准液 溶液, 100 μg/mL in heptane, ampule of 1 mL, Cerilliant®

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C-153

大麻酚酸（CBNA） 溶液, 1.0 mg/mL in acetonitrile, certified reference material, ampule of 1 mL, Cerilliant®

T-111

四氢次大麻酚酸（THCVA） 溶液, 1.0 mg/mL in acetonitrile, certified reference material, ampule of 1 mL, Cerilliant®

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大麻环酸(CBLA)标准液 溶液, 0.5 mg/mL in acetonitrile, certified reference material, ampule of 1 mL, Cerilliant®

C-180

7-Hydroxy cannabidiol (7-OH-CBD) solution, 1 mg/mL in methanol, certified reference material, ampule of 1 mL, Cerilliant®

C-217

Hemp Compliance Mix solution, certified reference material, ampule of 1 mL, Cerilliant®

C-219

Cannabinoid Mixture (Neutrals) - 8 Component solution, 500 μg/mL in methanol (each analyte), certified reference material, ampule of 1 mL, Cerilliant®

T-151

THC-O-Acetate solution, 1 mg/mL in methanol, certified reference material, ampule of 1 mL, Cerilliant®

C-181

7-Carboxy cannabidiol (7-COOH-CBD) solution, 1 mg/mL in methanol, certified reference material, ampule of 1 mL, Cerilliant®

C-220

Cannabinoid Mixture - 3 Component solution, 1 mg/mL in methanol ((each analyte)), certified reference material, ampule of 1 mL, Cerilliant®

C-218

Cannabinoid Mixture (Acids) - 6 Component solution, 500 μg/mL (1% DIPEA and 0.05% Ascorbic acid in Acetonitrile,each analyte), certified reference material, ampule of 1 mL, Cerilliant®

C-223

7-Hydroxy cannabidiol-D3 (7-OH-CBD-D3) solution, 100 μg/mL in methanol, certified reference material, ampule of 1 mL, Cerilliant®

C-224

7-Carboxy cannabidiol-D3 (7-COOH-CBD-D3) solution, 100 μg/mL in methanol, certified reference material, ampule of 1 mL, Cerilliant®

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11-Nor-9-carboxy-delta9-THCV solution, 100 μg/mL in methanol, certified reference material, ampule of 1 mL, Cerilliant®

C-244

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C-240

Cannabidiphorol (CBDP) solution, 1 mg/mL (1% DIPEA and 0.05% Ascorbic Acid in Acetonitrile), certified reference material, ampule of 1 mL, Cerilliant®

C-254

6-Hydroxy cannabidiol (6-OH-CBD) solution, 1 mg/mL (Degassed Acetonitrile), certified reference material, ampule of 1 mL, Cerilliant®

C-228

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H-158

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C-264

大麻环酸(CBLA)标准液 溶液, 0.5 mg/mL (0.1% DIPEA, 0.05 Ascorbic Acid in Acetonitrile), certified reference material, ampule of 1 mL, Cerilliant®

T-182

THC-O-Acetate solution, 1 mg/mL in acetonitrile, certified reference material, ampule of 1 mL, Cerilliant®

C-255

6-Hydroxy cannabidiol-D3 (6-OH-CBD-D3) solution, 100 μg/mL (Degassed Acetonitrile), certified reference material, ampule of 1 mL, Cerilliant®

C-238

Cannabidiol-O-beta-D-glucuronide sodium salt solution, 100 μg/mL in methanol (as free carboxylate), certified reference material, ampule of 1 mL, Cerilliant®

警示用语：

Danger

危险分类

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

靶器官

Eyes,Central nervous system

WGK

WGK 2

闪点(°F)

49.5 °F

闪点(°C)

9.7 °C

法规信息

监管及禁止进口产品

分析证书(COA)

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R B Laprairie et al.
British journal of pharmacology, 172(20), 4790-4805 (2015-07-29)
Cannabidiol has been reported to act as an antagonist at cannabinoid CB1 receptors. We hypothesized that cannabidiol would inhibit cannabinoid agonist activity through negative allosteric modulation of CB1 receptors. Internalization of CB1 receptors, arrestin2 recruitment, and PLCβ3 and ERK1/2 phosphorylation
Raymond J M Niesink et al.
Addiction (Abingdon, England), 110(12), 1941-1950 (2015-08-04)
Between 2000 and 2005 the average percentage of Δ(9) -tetrahydrocannabinol (THC) in marijuana as sold in Dutch coffeeshops has increased substantially; the potency of domestic products (Nederwiet and Nederhasj) has particularly increased. In contrast with imported marijuana, Nederwiet hardly contained
R G Pertwee
British journal of pharmacology, 153(2), 199-215 (2007-09-11)
Cannabis sativa is the source of a unique set of compounds known collectively as plant cannabinoids or phytocannabinoids. This review focuses on the manner with which three of these compounds, (-)-trans-delta9-tetrahydrocannabinol (delta9-THC), (-)-cannabidiol (CBD) and (-)-trans-delta9-tetrahydrocannabivarin (delta9-THCV), interact with cannabinoid
Antonio Waldo Zuardi
Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999), 30(3), 271-280 (2008-10-04)
The aim of this review is to describe the historical development of research on cannabidiol. This review was carried out on reports drawn from Medline, Web of Science and SciELO. After the elucidation of the chemical structure of cannabidiol in
Alline Cristina Campos et al.
Psychopharmacology, 226(1), 13-24 (2012-09-26)
Cannabidiol (CBD) is a non-psychotomimetic constituent of Cannabis sativa plant that promotes antianxiety and anti-panic effects in animal models after acute systemic or intra-dorsal periaqueductal gray (DPAG) administration. However, the effects of CBD repeated administration, and the possible mechanisms involved
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