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Merck
CN

850375C

Avanti

18:1 (Δ9-Cis) PC (DOPC)

Avanti Research - A Croda Brand

别名:

1,2-二-(9Z-十八烯酰基)-sn-甘油-3-磷酸胆碱;DOPC;PC(18:1(9Z)/18:1(9Z))

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关于此项目

经验公式(希尔记法):
C44H84NO8P
化学文摘社编号:
分子量:
786.11
MDL number:
UNSPSC Code:
51191904
NACRES:
NA.25
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产品名称

18:1 (Δ9-Cis) PC (DOPC), Avanti Research - A Croda Brand

SMILES string

[P](=O)([O-])(OC[C@@H](OC(=O)CCCCCCC\C=C/CCCCCCCC)COC(=O)CCCCCCC\C=C/CCCCCCCC)OCC[N+](C)(C)C

InChI

1S/C44H84NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-43(46)50-40-42(41-52-54(48,49)51-39-38-45(3,4)5)53-44(47)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h20-23,42H,6-19,24-41H2,1-5H3/b22-20-,23-21-/t42-/m0/s1

InChI key

SNKAWJBJQDLSFF-AOMFJDGTSA-N

description

1,2-dioleoyl-sn-glycero-3-phosphocholine, chloroform

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (850375C-25mg)
pkg of 2 × 20 mL (850375C-1g)
pkg of 2 × 4 mL (850375C-200mg)
pkg of 5 × 4 mL (850375C-500mg)

manufacturer/tradename

Avanti Research - A Croda Brand

concentration

10 mg/mL (850375C-25mg)
25 mg/mL (850375C-1g)
25 mg/mL (850375C-200mg)
25 mg/mL (850375C-500mg)

lipid type

cardiolipins
phospholipids

shipped in

dry ice

storage temp.

−20°C

Application

18:1 (Δ9-Cis) PC (DOPC)已用于制备荧光显微镜的平面支撑脂质双层,还可用于制备原细胞。

Biochem/physiol Actions

18:1 (Δ9- 顺式 )PC (DOPC) 高度耐受二甲基亚砜 (DMSO) 的毒性作用。

General description

Avanti提供的磷脂酰胆碱产品列表旨在提供具有多种物理性质的化合物。可选产品包括短链(C3-C8是水溶性和吸湿性的)、饱和、多不饱和和混合酸PC。′所有产品均通过HPLC纯化,并采取特殊预防措施保护产品不发生氧化和水解。

Packaging

30 mL棕色窄口螺旋盖玻璃瓶(850375C-1g)
5 mL 透明玻璃密封安瓿 (850375C-200 mg)
5 mL 透明玻璃密封安瓿 (850375C-25mg)
5 mL 透明玻璃密封安瓿 (850375C-500mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system, Liver,Kidney

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

危险化学品
易制毒化学品(2类)
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Molecular dynamics simulations of the interactions of DMSO with DPPC and DOPC phospholipid membranes
Hughes ZE, et al.
The Journal of Physical Chemistry B, 116(39), 11911-11923 (2012)
Mesoporous silica-supported lipid bilayers (protocells) for DNA cargo delivery to the spinal cord
Dengler EC, et al.
Journal of Controlled Release : Official Journal of the Controlled Release Society, 168(2), 209-224 (2013)
K-Ras4B remains monomeric on membranes over a wide range of surface densities and lipid compositions
Chung JK, et al.
Biophysical Journal, 114(1), 137-145 (2018)
Tatiana K Rostovtseva et al.
The Journal of biological chemistry, 287(35), 29589-29598 (2012-07-06)
Elucidating molecular mechanisms by which lipids regulate protein function within biological membranes is critical for understanding the many cellular processes. Recently, we have found that dimeric αβ-tubulin, a subunit of microtubules, regulates mitochondrial respiration by blocking the voltage-dependent anion channel
Orrin Shindell et al.
Langmuir : the ACS journal of surfaces and colloids, 34(15), 4673-4680 (2018-01-25)
Artificial lipid membranes incorporating proteins have frequently been used as models for the dynamic organization of biological structures in living cells as well as in the development of biology-inspired technologies. We report here on the experimental demonstration and characterization of

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