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关于此项目
经验公式（希尔记法）:
C36H51BF2N2O
化学文摘社编号:
分子量:
576.61
MDL number:
NACRES:
NA.25
UNSPSC Code:
12352211
description
23-(dipyrrometheneboron difluoride)-24-norcholesterol
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (810255P-1mg), pkg of 1 × 10 mg (810255P-10mg), pkg of 1 × 5 mg (810255P-5mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand
shipped in
dry ice
storage temp.
−20°C
General description
附着在BODIPY上的生物分子在可见光下很容易被吸收。它导致更大的荧光量子产率。它具有很高的光稳定性，并且对极性和pH的变化不太敏感。
Application
TOPFLUOR™适用于:
- 胆固醇摄取测定
- 在活细胞实验中用于BODIPY胆固醇标记
- 通过聚乙烯醇（PVA）辅助的脂质溶胀形成巨大的Janus脂质体
Biochem/physiol Actions
BODIPY标记的胆固醇具有与天然胆固醇相似的特性。它可充当活细胞的胆固醇标志物，并有助于运输细胞内的胆固醇。它也可能有助于指示脂质储存疾病。
Packaging
5 mL棕色玻璃螺旋盖小瓶（810255P-10mg）
5 mL棕色玻璃螺旋盖小瓶（810255P-1mg）
5 mL棕色玻璃螺旋盖小瓶（810255P-5mg）
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
TopFluor is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
wgk
WGK 3
商品
Explore full-spectrum fluorophores, fluorescent lipids, and probes for imaging, membrane studies, and labeling with TopFluor™, squaraines, and more.
James E Shaw et al.
Biophysical journal, 90(6), 2170-2178 (2005-12-20)
Coupling atomic force microscopy (AFM) with high-resolution fluorescence microscopy is an attractive means of identifying membrane domains by both physical topography and fluorescence. We have used this approach to study the ability of a suite of fluorescent molecules to probe
Functional inhibition of acid sphingomyelinase disrupts infection by intracellular bacterial pathogens
Cockburn CL, et al.
Life science alliance, 2(2), e201800292-e201800292 (2019)
Jameson T Crowley et al.
PLoS pathogens, 9(1), e1003109-e1003109 (2013-01-18)
Borrelia burgdorferi, the agent of Lyme disease, has cholesterol and cholesterol-glycolipids that are essential for bacterial fitness, are antigenic, and could be important in mediating interactions with cells of the eukaryotic host. We show that the spirochetes can acquire cholesterol
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 810255P-1MG | 04061835185634 |
| 810255P-5MG | 04061835185641 |
| 810255P-10MG | 04061835185627 |