推荐产品
检测方案
>99% (TLC)
形式
powder
包装
pkg of 1 × 100 μg (with stopper and crimp cap (850154P-100ug))
pkg of 1 × 500 μg (with stopper and crimp cap (850154P-500ug))
制造商/商品名称
Avanti Polar Lipids 850154P
脂质类型
phospholipids
cardiolipins
运输
dry ice
储存温度
−20°C
SMILES字符串
[H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](OP(O)([O-])=O)[C@H](O)[C@@H](OP([O-])(O)=O)[C@H]1O)=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[NH4+].[NH4+].[NH4+]
一般描述
磷脂酰肌醇3,5-二磷酸酯(PI(3,5)P2)是一种磷酸肌醇肌醇磷脂,主要存在于真菌和高等真核生物的内体和溶酶体膜中。
肌醇磷脂物质是膜结合的信号分子,它参与细胞生理学的几乎所有方面,包括细胞生长、代谢、增殖和存活。
应用
18:1 PI(3,5)P2(1,2-二油酰基-sn-甘油-3-磷酸-(1′-肌醇-3′,5′-双磷酸酯)(铵盐))可用于囊泡用于共沉降测定。它可用于:
- 脂质覆盖测定
- 脂质体共沉淀测定
- 脂质体浮选测定
生化/生理作用
磷脂酰肌醇3,5-双磷酸酯(PI(3,5)P2)的水平响应许多细胞外应激而激增。
包装
带塞子和压接盖的2 mL棕色血清瓶(850154P-100ug)
带塞子和压接盖的2 mL棕色血清瓶(850154P-500ug)
通常也和此产品一起购买
产品编号
说明
价格
WGK
WGK 3
闪点(°F)
No data available
闪点(°C)
No data available
Molecular biology of the cell, 25(8), 1251-1262 (2014-02-14)
Vacuolar proton-translocating ATPases (V-ATPases) are highly conserved, ATP-driven proton pumps regulated by reversible dissociation of its cytosolic, peripheral V1 domain from the integral membrane V(o) domain. Multiple stresses induce changes in V1-V(o) assembly, but the signaling mechanisms behind these changes
The Journal of biological chemistry, 293(13), 4818-4829 (2018-02-10)
Membrane phosphoinositides control organization and dynamics of the actin cytoskeleton by regulating the activities of several key actin-binding proteins. Twinfilin is an evolutionarily conserved protein that contributes to cytoskeletal dynamics by interacting with actin monomers, filaments, and the heterodimeric capping
The Journal of biological chemistry, 288(28), 20633-20645 (2013-06-05)
Glucose/carbon metabolism is a fundamental cellular process in living cells. In response to varying environments, eukaryotic cells reprogram their glucose/carbon metabolism between aerobic or anaerobic glycolysis, oxidative phosphorylation, and/or gluconeogenesis. The distinct type of glucose/carbon metabolism that a cell carries
Neuron, 98(2), 335-349 (2018-04-03)
Rapid and efficient synaptic vesicle fusion requires a pool of primed vesicles, the nearby tethering of Ca2+ channels, and the presence of the phospholipid PIP2 in the target membrane. Although the presynaptic active zone mediates the first two requirements, it
The Journal of cell biology, 214(5), 517-527 (2016-08-24)
Macropinocytosis, the internalization of extracellular fluid and material by plasma membrane ruffles, is critical for antigen presentation, cell metabolism, and signaling. Macropinosomes mature through homotypic and heterotypic fusion with endosomes and ultimately merge with lysosomes. The molecular underpinnings of this
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