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M2780

Sigma-Aldrich

N 6 -甲基腺苷 5′-单磷酸 钠盐

≥97% (HPLC)

别名:

6-Me-5′-AMP, N-甲基-5′-腺苷酸二钠盐

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1 EA
CN¥6,110.23

CN¥6,110.23

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1 EA
CN¥6,110.23

About This Item

线性分子式:
C11H15N5O7PNa
CAS号:
81921-35-9
分子量:
383.23
UNSPSC代码:
41106305
PubChem化学物质编号:
24896766

CN¥6,110.23

请联系客服了解存货情况
获取大包装报价

方案

≥97% (HPLC)

储存温度

−20°C

SMILES字符串

[Na].CNc1ncnc2n(cnc12)C3OC(COP(O)(O)=O)C(O)C3O

InChI

1S/C11H16N5O7P.2Na/c1-12-9-6-10(14-3-13-9)16(4-15-6)11-8(18)7(17)5(23-11)2-22-24(19,20)21;;/h3-5,7-8,11,17-18H,2H2,1H3,(H,12,13,14)(H2,19,20,21);;/q;2*+1/p-2/t5-,7-,8-,11-;;/m1../s1

InChI key

HFOKUKRAZPHTHH-LYYWGVPGSA-L

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此商品
28476U28466U28467U
SLB®-5ms Capillary GC Column L × I.D. 20 m × 0.18 mm, df 0.18 μm

28564U

SLB®-5ms Capillary GC Column

SLB®-5ms Capillary GC Column L × I.D. 30 m × 0.25 mm, df 1.00 μm

28476U

SLB®-5ms Capillary GC Column

SLB®-5ms Capillary GC Column L × I.D. 15 m × 0.10 mm, df 0.10 μm

28466U

SLB®-5ms Capillary GC Column

SLB®-5ms Capillary GC Column L × I.D. 30 m × 0.25 mm, df 0.10 μm

28467U

SLB®-5ms Capillary GC Column

df

0.18 μm

df

1.00 μm

df

0.10 μm

df

0.10 μm

parameter

-60-340 °C temperature (isothermal), -60-360 °C temperature (programmed)

parameter

-60-340 °C temperature (isothermal), -60-360 °C temperature (programmed)

parameter

-60-340 °C temperature (isothermal), -60-360 °C temperature (programmed)

parameter

-60-340 °C temperature (isothermal), -60-360 °C temperature (programmed)

material

fused silica

material

fused silica

material

fused silica

material

fused silica

technique(s)

GC/MS: suitable, gas chromatography (GC): suitable (fast GC)

technique(s)

GC/MS: suitable, gas chromatography (GC): suitable

technique(s)

GC/MS: suitable, gas chromatography (GC): suitable (fast GC)

technique(s)

GC/MS: suitable, gas chromatography (GC): suitable

application(s)

agriculture
chemicals and industrial polymers
cleaning products
clinical
cosmetics
environmental
flavors and fragrances
food and beverages
forensics and toxicology
industrial hygiene
life science and biopharma
personal care
petroleum
pharmaceutical (small molecule)

application(s)

agriculture
chemicals and industrial polymers
cleaning products
clinical
cosmetics
environmental
flavors and fragrances
food and beverages
forensics and toxicology
industrial hygiene
life science and biopharma
personal care
petroleum
pharmaceutical (small molecule)

application(s)

agriculture
chemicals and industrial polymers
cleaning products
clinical
cosmetics
environmental
flavors and fragrances
food and beverages
forensics and toxicology
industrial hygiene
life science and biopharma
personal care
petroleum
pharmaceutical (small molecule)

application(s)

agriculture
chemicals and industrial polymers
cleaning products
clinical
cosmetics
environmental
flavors and fragrances
food and beverages
forensics and toxicology
industrial hygiene
life science and biopharma
personal care
petroleum
pharmaceutical (small molecule)

应用

N6-甲基腺苷 5′-单磷酸钠盐可以用于N6-甲基腺苷(m6A) 核糖核蛋白酶免疫沉淀反应。[1]m6A在近几年获得了许多关注，因为m6A mRNA修饰在mRNA稳定和转译效率中起到作用。[2][3]

生化/生理作用

一种糖原磷酸化酶 b 活化剂。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

  • 技术规格说明书

    • 历史批次信息供参考:

    分析证书(COA)

    Lot/Batch Number
    0000377104
    0000349428
    0000310744
    0000310744
    0000349428

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    M Morange et al.
    European journal of biochemistry, 65(2), 553-563 (1976-06-01)
    A series of AMP analogs has been selected in order to better understand the structural requirements (a) for the efficient binding of the activator molecule at the correct site on phosphorylase b from rabbit skeletal muscle and (b) for the
    N6-methyladenosine is required for the hypoxic stabilization of specific mRNAs.
    Fry N J, et al.
    RNA, 23(9), 1444-1455 (2017)
    N(6)-methyladenosine Modulates Messenger RNA Translation Efficiency.
    Wang X, et al.
    Cell, 161(6), 1388-1399 (2015)
    Fengchao Lang et al.
    PLoS pathogens, 15(6), e1007796-e1007796 (2019-06-22)
    Epstein-Barr virus (EBV) is a ubiquitous oncogenic virus that induces many cancers. N6-Methyladenosine (m6A) modification regulates many cellular processes. We explored the role of m6A in EBV gene regulation and associated cancers. We have comprehensively defined m6A modification of EBV
    Leilei Zhou et al.
    Genome biology, 20(1), 156-156 (2019-08-08)
    Methylation of nucleotides, notably in the forms of 5-methylcytosine (5mC) in DNA and N6-methyladenosine (m6A) in mRNA, carries important information for gene regulation. 5mC has been elucidated to participate in the regulation of fruit ripening, whereas the function of m6A
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