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Merck
CN

L1002

Sigma-Aldrich

L-亮氨酸甲酯 盐酸盐

98%, for peptide synthesis

别名:

(S)-2-Amino-4-methylpentanoic acid methyl ester hydrochloride, L-Leu-OMe·HCl

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About This Item

线性分子式:
(CH3)2CHCH2CH(NH2)COOCH3 · HCl
CAS号:
分子量:
181.66
Beilstein:
3595133
EC 号:
MDL编号:
UNSPSC代码:
12352209
eCl@ss:
32160406
PubChem化学物质编号:
NACRES:
NA.22

产品名称

L-亮氨酸甲酯 盐酸盐, 98%

质量水平

方案

98%

表单

powder or crystals

旋光性

[α]22/D +13°, c = 2 in H2O

反应适用性

reaction type: solution phase peptide synthesis

颜色

white

mp

151-153 °C (lit.)

应用

peptide synthesis

SMILES字符串

Cl[H].COC(=O)[C@@H](N)CC(C)C

InChI

1S/C7H15NO2.ClH/c1-5(2)4-6(8)7(9)10-3;/h5-6H,4,8H2,1-3H3;1H/t6-;/m0./s1

InChI key

DODCBMODXGJOKD-RGMNGODLSA-N

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储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Stephanie M Krasnow et al.
Journal of neuroinflammation, 14(1), 133-133 (2017-07-03)
During acute infections and chronic illnesses, the pro-inflammatory cytokine interleukin-1β (IL-1β) acts within the brain to elicit metabolic derangements and sickness behaviors. It is unknown which cells in the brain are the proximal targets for IL-1β with respect to the
Gautam K Gandhi et al.
ASN neuro, 2(2), e00030-e00030 (2010-04-17)
Sensory and cognitive impairments have been documented in diabetic humans and animals, but the pathophysiology of diabetes in the central nervous system is poorly understood. Because a high glucose level disrupts gap junctional communication in various cell types and astrocytes
D R Brown et al.
Nature, 380(6572), 345-347 (1996-03-28)
The prion protein PrPc is a glycoprotein of unknown function normally found in neurons and glia. It is involved in diseases such as bovine spongiform encephalopathy (BSE), scrapie and Creutzfeldt-Jakob disease. PrPSc, an altered isoform of PrPC that is associated
A Giese et al.
Brain pathology (Zurich, Switzerland), 8(3), 449-457 (1998-07-21)
To elucidate the role played by the prion protein in scrapie pathogenesis, we performed experiments with PrP27-30 isolated from scrapie-infected hamster brains in cell culture and studied in vivo the temporal and spatial correlation between deposition of the disease-associated isoform
Simon M Cool et al.
Stem cells and development, 14(6), 632-642 (2006-01-26)
Therapeutic modalities aimed at bone regeneration are increasingly employing extracellular matrix (ECM) constituents to control bone marrow progenitor cell (BMPC) commitment, growth, and differentiation. However, the precise role these ECM elements play during stem cell differentiation remains unclear. (See also

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