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线性分子式:
[-(CH2)4CO2(CH2)3CH3]2
化学文摘社编号:
分子量:
314.46
UNSPSC Code:
12162002
NACRES:
NA.23
PubChem Substance ID:
EC Number:
203-672-5
Beilstein/REAXYS Number:
1798308
MDL number:
InChI key
PYGXAGIECVVIOZ-UHFFFAOYSA-N
InChI
1S/C18H34O4/c1-3-5-15-21-17(19)13-11-9-7-8-10-12-14-18(20)22-16-6-4-2/h3-16H2,1-2H3
SMILES string
CCCCOC(=O)CCCCCCCCC(=O)OCCCC
grade
technical grade
form
liquid
bp
178-179 °C/3 mmHg (lit.)
solubility
hexane, toluene, ethanol and acetone: soluble, water and propylene glycol: insoluble
density
0.936 g/mL at 25 °C (lit.)
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General description
Dibutyl sebacate(DBS) is a lipophilic dibutyl ester that can be used as a plasticizer with low solubility in water.
Application
DBS can be used as a plasticizer for the formation of ethylcellulose based coating membranes which can be potentially used in drug delivery systems. It may also be used as a plasticizer during the fabrication of electronic artificial tongue sensors for analyzing the intensity of olive oils.
存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
366.8 °F - open cup
flash_point_c
186 °C - open cup
ppe
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
GC method for determining polyadipate plasticizers in foods: transesterification to dibutyl adipate, conversion to migrating polyadipate.
Biedermann M and Grob K
Chromatographia, 64(9-10), 543-552 (2006)
Sensory intensity assessment of olive oils using an electronic tongue.
Veloso ACA, et al.
Talanta, 146(3), 585-593 (2016)
Physico-mechanical analysis of free ethylcellulose films plasticized with incremental weight percents of dibutyl sebacate.
Kangarlou S and Haririan I
Iranian Journal of Pharmaceutical Sciences, 3(3), 135-142 (2007)
Thomas Quinten et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 71(1), 145-154 (2008-05-31)
The aim of this study was to develop sustained-release matrix tablets by means of injection moulding and to evaluate the influence of process temperature, matrix composition (EC and HPMC concentration) and viscosity grade of ethylcellulose (EC) and hydroxypropylmethylcellulose (HPMC) on
Kangarlou Sogol et al.
International journal of pharmaceutics, 408(1-2), 1-8 (2010-11-26)
The object of this study was to investigate the influence of static and dynamic forces on mechanical properties of the biocompatible polymer ethyl cellulose. Similar polymeric films containing 40% (w/w) of the plasticizer dibutyl sebacate were subjected to tensile forces
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