C121908
L-半胱氨酸乙酯 盐酸盐
98%, for peptide synthesis
别名:
(R)-Ethyl 2-amino-3-mercaptopropanoate hydrochloride, Cystanin, Ethyl L-cysteinate hydrochloride
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所有图片(1)
About This Item
线性分子式:
HSCH2CH(NH2)COOC2H5 · HCl
CAS号:
分子量:
185.67
Beilstein:
3562600
EC 号:
MDL编号:
UNSPSC代码:
12352209
eCl@ss:
32160406
PubChem化学物质编号:
NACRES:
NA.22
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产品名称
L-半胱氨酸乙酯 盐酸盐, 98%
质量水平
方案
98%
表单
powder
旋光性
[α]20/D −7.9°, c = 1 in 1 M HCl
光学纯度
ee: 99% (GLC)
反应适用性
reaction type: solution phase peptide synthesis
颜色
white
mp
123-125 °C (lit.)
应用
peptide synthesis
SMILES字符串
Cl[H].CCOC(=O)[C@@H](N)CS
InChI
1S/C5H11NO2S.ClH/c1-2-8-5(7)4(6)3-9;/h4,9H,2-3,6H2,1H3;1H/t4-;/m0./s1
InChI key
JFKJWWJOCJHMGV-WCCKRBBISA-N
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相关类别
储存分类代码
11 - Combustible Solids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Krum Kafedjiiski et al.
International journal of pharmaceutics, 343(1-2), 48-58 (2007-06-05)
It was the aim of this study to synthesize and characterize a novel hyaluronic acid-cysteine ethyl ester (HA-Cys) conjugate providing improved mucoadhesive properties and a significantly lowered biodegradation rate. Mediated by carbodiimide and N-hydroxysuccinimide, L-cysteine ethyl ester hydrochloride was covalently
Laura L Perissinotti et al.
Journal of the American Chemical Society, 127(2), 486-487 (2005-01-13)
We report an investigation of the reaction between (S)-nitroso-l-cysteine ethyl ester and l-cysteine ethyl ester as a model of physiologically relevant transnitrosation processes. Our theoretical and experimental evidence clearly supports the existence of a nitroxyl disulfide intermediate in solution.
Dimitrios Tsikas et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 877(28), 3442-3455 (2009-07-15)
S-Nitrosothiols from low-molecular-mass and high-molecular-mass thiols, including glutathione, albumin and hemoglobin, are endogenous potent vasodilators and inhibitors of platelet aggregation. By utilizing the S-transnitrosation reaction and by using the lipophilic (pK(L) 0.78) and strong nucleophilic synthetic thiol N-acetyl cysteine ethyl
M Hisadome et al.
Japanese journal of pharmacology, 53(1), 57-66 (1990-05-01)
L-Cysteine ethylester hydrochloride (Cystanin, ethylcysteine) at doses of 3-30 mg/kg, p.o., potentiated the reduction of nitroblue tetrazolium (NBT) by mouse peritoneal macrophages ex vivo. In in vitro experiments, this drug (30 microM) augmented NBT reduction of mouse peritoneal macrophages induced
Ewa Mironiuk-Puchalska et al.
Nucleosides, nucleotides & nucleic acids, 31(1), 72-84 (2012-01-20)
The novel aza-analogues of tiazofurin (TZF) with 2-[5,5-bis(hydroxymethyl)pyrrolidin-2-yl] moiety, as sugar mimic, were synthesized from O,O-cyclohexylidene derivative of 4,4-bis(hydroxymethyl)-4-nitrobutanal in multi-gram scale. The synthetic route consisted of three stages: (i) the synthesis of corresponding derivative of 5,5-bis(hydroxymethyl)pyrrolidine-2-carbonitrile, (ii) the construction
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