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B10102

Sigma-Aldrich

苯并[e]芘

98%

别名:

1,2-苯并芘, 4,5-苯并芘

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About This Item

经验公式（希尔记法）:
C20H12
CAS号:
192-97-2
分子量:
252.31
Beilstein:
1911334
EC 号:
205-892-7
MDL编号:
MFCD00003605
UNSPSC代码:
12352103
PubChem化学物质编号:
24891539
NACRES:
NA.23

质量水平

100

方案

98%

表单

crystals

mp

177-180 °C (lit.)

SMILES字符串

c1ccc2c(c1)c3cccc4ccc5cccc2c5c34

InChI

1S/C20H12/c1-2-8-16-15(7-1)17-9-3-5-13-11-12-14-6-4-10-18(16)20(14)19(13)17/h1-12H

InChI key

TXVHTIQJNYSSKO-UHFFFAOYSA-N

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相关类别

一般描述

这种多环芳烃可溶于丙酮。它是一种非致癌的苯并芘异构体。 研究显示，它在体内和体外暴露后无免疫抑制活性。在自然界中，它被秀丽隐杆线虫菌株代谢为3-苯并[e]芘硫酸盐、1-羟基-3-苯并[e]芘基硫酸盐和苯并[e]芘3-O-β-吡喃葡萄糖苷。

应用

用于研究苯并[e]芘对DNP-Ficoll和绵羊红细胞的抗体反应的免疫抑制活性 以及从水样中提取有机化合物的“分散液-液微萃取”技术。

象形图

Health hazardEnvironment
GHS08,GHS09

警示用语：

Danger

危险声明

H350,H410

预防措施声明

P201 - P273 - P308 + P313

危险分类

Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1B

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

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分析证书(COA)

Lot/Batch Number
MKCR8964
MKCP5010
MKCF2578
MKBX6087V
MKBX2505V

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Mohammad Rezaee et al.
Journal of chromatography. A, 1116(1-2), 1-9 (2006-04-01)
A new microextraction technique termed dispersive liquid-liquid microextraction (DLLME) was developed. DLLME is a very simple and rapid method for extraction and preconcentration of organic compounds from water samples. In this method, the appropriate mixture of extraction solvent (8.0 microL
K L White et al.
Cancer research, 44(8), 3388-3393 (1984-08-01)
The role of metabolic activation of benzo(a)pyrene B(a)P in mediating its suppression of humoral immune responsiveness of the female C57BL/6 X C3H F1 (hereafter called B6C3F1) mouse was addressed in these studies. The model was the in vitro antibody response
W H Houser et al.
Molecular carcinogenesis, 5(3), 232-237 (1992-01-01)
In the rat, expression of the CYP1A1 gene is closely associated with arylhydrocarbon hydroxylase (AHH) enzyme activity. AHH is an inducile enzyme activity known to play an important role in the bioactivation of polycyclic aromatic hydrocarbons (PAHs) to mutagenic and
Saffar Mansoor et al.
Investigative ophthalmology & visual science, 51(5), 2601-2607 (2009-12-05)
To study the inhibitory effects of some agents or drugs (inhibitors) on benzo(e)pyrene (B(e)P)-induced cell death and apoptosis on human retinal pigment epithelial (ARPE-19) cells in vitro. ARPE-19 cells were pretreated with varying concentrations of different classes of inhibitors (calpain
D F Lewis et al.
Toxicology letters, 71(3), 235-243 (1994-05-01)
The present studies were undertaken to provide a rationale for the observation that benzo(a)pyrene and 2-acetylaminofluorene induce the hepatic CYP1A1 protein, whereas their non-carcinogenic isomers benzo(e)pyrene and 4-acetylaminofluorene are, at best, relatively very weak inducers. Using amino acid sequence alignment
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