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Merck
CN

928348

Sigma-Aldrich

BrettPhos ChemBeads

别名:

2-(Dicyclohexylphosphino)3,6-dimethoxy-2′,4′,6′-triisopropyl-1,1′-biphenyl

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About This Item

经验公式(希尔记法):
C35H53O2P
分子量:
536.77
MDL编号:
UNSPSC代码:
12352112
NACRES:
NA.82

表单

solid

质量水平

组成

~ 5 wt.% loading of catalyst

反应适用性

reagent type: catalyst
reaction type: Cross Couplings

SMILES字符串

P(C4CCCCC4)(C3CCCCC3)c1c(ccc(c1c2c(cc(cc2C(C)C)C(C)C)C(C)C)OC)OC

InChI

1S/C35H53O2P/c1-23(2)26-21-29(24(3)4)33(30(22-26)25(5)6)34-31(36-7)19-20-32(37-8)35(34)38(27-15-11-9-12-16-27)28-17-13-10-14-18-28/h19-25,27-28H,9-18H2,1-8H3

InChI key

WDVGNXKCFBOKDF-UHFFFAOYSA-N

应用

BrettPhos is a dialkylbiaryl phosphine ligand developed by the Buchwald group. It promotes cross-coupling reactions more efficiently and exhibits improved reactivity compared to other catalytic systems.


It can be used in:
  • palladium-catalyzed trifluoromethylation of aryl chlorides
  • Buchwald-Hartwig amination
  • synthesis of 4-aryl and alkyl substituted, N6-alkylated pyridazine-3,6-diamines via a Buchwald protocol
ChemBeads are chemical coated glass beads. ChemBeads offer improved flowability and chemical uniformity perfect for automated solid dispensing and high-throughput experimentation. The method of creating ChemBeads uses no other chemicals or surfactants allowing the user to accurately dispense sub-milligram amounts of chemical.

Learn more about ChemBeads products

For larger scale uses, product also available in powdered form (718742)

象形图

Health hazard

警示用语:

Danger

危险声明

危险分类

Carc. 1B Inhalation

储存分类代码

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 1

法规信息

新产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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商品

ChemBeads, catalyst-coated glass beads, dispense solid chemical reagents for nanomole-scale high-throughput reaction screening.

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