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Merck
CN

913650

Sigma-Aldrich

Polyoxyethylene bis(azide) solution

average Mn 450, 0.1 g/mL in THF

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别名:
O,O′-Bis(2-azidoethyl)polyethylene glycol, PEG-diazide
线性分子式:
N3(C2H4O)nC2H4N3
UNSPSC代码:
12352125
NACRES:
NA.23

形式

liquid

质量水平

分子量

PEG ~400 Da
average Mn 450

浓度

0.1 g/mL in THF

颜色

pale yellow

储存温度

2-8°C

应用

PEG for cross-linking and used in "click" chemistry reactions. PEGylated materials have found broad use in drug delivery systems, virology, and immunology, as the incorporation of PEG improves pharmacological properties such as increased water solubility, enhanced resistance to degradation (protein hydrolysis), increased circulation half-life, and reduced antigenicity. Polymer for preparing enzyme conjugates soluble in organic solvents; promising drug carrier.

警示用语:

Danger

危险分类

Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

靶器官

Central nervous system, Respiratory system

补充剂危害

WGK

WGK 3

闪点(°F)

0.5 °F

闪点(°C)

-17.5 °C

法规信息

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Improving the tensile strength of carbon nanotube yarn via one-step double [2+1] cycloadditions.
H Kim, et al.
Korean Journal of Chemical Engineering, 33(1), 299-304 (2016)
Shao Qiong Liu et al.
Biomaterials, 30(8), 1453-1461 (2008-12-23)
In this study, biodegradable PEG-peptide hydrogels have been synthesized using Click chemistry. A series of Arg-Gly-Asp (RGD) containing peptides were prepared via a solid phase synthesis approach, which were further functionalized with azide to yield peptide azide or peptide diazide.
Tilman Läppchen et al.
European journal of medicinal chemistry, 89, 279-295 (2014-12-03)
Calixarene 0118 is a potent anti-angiogenic agent that effectively inhibited tumor growth in preclinical studies, and is currently being evaluated in a phase I clinical trial. We have designed two close mimetics of calixarene 0118 containing a terminal alkynyl-functional group

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