表单
liquid
反应适用性
reaction type: Coupling Reactions
浓度
1 M in THF
密度
0.870 g/mL
应用
peptide synthesis
SMILES字符串
N(=C=NC(C)C)C(C)C
InChI
1S/C7H14N2/c1-6(2)8-5-9-7(3)4/h6-7H,1-4H3
InChI key
BDNKZNFMNDZQMI-UHFFFAOYSA-N
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应用
肽合成的偶联剂。
DIC (N,N′-Diisopropylcarbodiimide) has been used in combination with 1-hydroxy-7-azabenzotriazole (HOAt) for the coupling of amino acid with N-allylglycine to form N-allylpeptide.
Valuable reagent offered as a solution in tetrahydrofuran for more convenient handling.
警示用语:
Danger
危险分类
Acute Tox. 2 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Resp. Sens. 1 - Skin Sens. 1 - STOT SE 3
靶器官
Respiratory system
补充剂危害
储存分类代码
3 - Flammable liquids
WGK
WGK 3
闪点(°F)
2.0 °F
闪点(°C)
-16.66 °C
法规信息
危险化学品
此项目有
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J Izdebski et al.
International journal of peptide and protein research, 43(2), 184-189 (1994-02-01)
Alkoxycarbonylamino acid symmetrical anhydrides were allowed to react with N,N'-diisopropylcarbodiimide. The determination of the decrease in carbodiimide concentration indicated that the reaction was slow and proceeded indirectly. It is presumed that symmetrical anhydride in the presence of basic carbodiimide is
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