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Merck
CN
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主要文件

901186

Sigma-Aldrich

吡啶基二硫化甲基丙烯酸乙酯

≥98.0%, contains 150 ppm MEHQ as inhibitor

别名:

2-甲基二吡啶基二甲基丙烯酸酯, PDSEMA

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About This Item

经验公式(希尔记法):
C11H13NO2S2
分子量:
255.36
MDL编号:
UNSPSC代码:
12352005
NACRES:
NA.23

方案

≥98.0%

表单

liquid

包含

150 ppm MEHQ as inhibitor

颜色

colorless to pale yellow

运输

wet ice

储存温度

−20°C

一般描述

吡啶基二硫化甲基丙烯酸乙酯是一种基于甲基丙烯酸酯的单体,用于合成聚(吡啶基二硫化甲基丙烯酸乙酯)[p(PDSMA)]和其他共聚物。p(PDSMA)包含一个受保护的侧基硫醇,可用于通过硫醇-二硫键交换反应进行聚合后官能化。另外,反应进程通常可以通过吸收光谱法进行监测,因为释放的 2-吡啶硫酮的光谱特征(λ max= 375 nm)与聚合物中的吡啶基二硫化官能度(λ max= 280 nm)明显不同。由于它们的多功能性,这些材料已用于多种生物医学应用中,例如聚合物-生物分子缀合物的合成和药物递送应用。

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2

储存分类代码

10 - Combustible liquids

WGK

WGK 3

闪点(°F)

230.0 °F

闪点(°C)

110 °C


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Nicholas M Matsumoto et al.
Polymer chemistry, 4(8), 2464-2469 (2014-04-25)
The covalent conjugation of bovine serum albumin (BSA) to disulfide cross-linked polymeric nanogels is reported. Polymeric nanogel precursors were synthesized via a reversible addition-fragmentation chain transfer (RAFT) random copolymerization of poly(ethylene glycol) methyl ether methacrylate (PEGMA) and pyridyl disulfide methacrylate
Xiaotian Ji et al.
Colloids and surfaces. B, Biointerfaces, 148, 41-48 (2016-11-05)
In this paper a novel method for the fabrication of hybrid nanogels based on thiol-disulfide exchange reaction is reported. Poly(oligo(ethylene glycol) monomethyl ether methacrylate-co-di(ethylene glycol) methyl ether methacrylate-co-2-(2-pyridyldisulfide) ethyl methacrylate) (POEGMA-co-PDEGMA-co-PDSMA) was synthesized by reversible addition-fragmentation chain transfer polymerization. Pyridyl
Reactive Copolymers Based on N-Vinyl Lactams with Pyridyl Disulfide Side Groups via RAFT Polymerization and Postmodification via Thiol-Disulfide Exchange Reaction.
Peng H, et al.
Macromolecules, 49(19), 7141-7154 (2016)
Judy Ventura et al.
Biomacromolecules, 16(10), 3161-3171 (2015-09-04)
Conjugation of biologically active proteins to polymeric materials is of great interest in the treatment of cancer and other diseases of protein deficiency. The conjugation of such biomacromolecules is challenging both due to their hydrophilicity and propensity to denature under
Simultaneous and Reversible Functionalization of Copolymers for Biological Applications.
Ghosh S, et al.
Macromolecules, 39(17), 5595-5597 (2006)

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